Tamai Naotaka, Shinjoh Masayoshi, Oikawa Hiroyuki, Hamada Riku, Morio Tomohiro, Koinuma Goro, Takahashi Takao
Department of Pediatrics, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Pediatrics, Ariake child clinic, Ariake Garden Medical Mall 1F, 2-1-7 Ariake, Koto-ku, Tokyo 135-0063, Japan.
Radiol Case Rep. 2024 Feb 3;19(4):1642-1645. doi: 10.1016/j.radcr.2024.01.048. eCollection 2024 Apr.
Invasive pneumococcal disease typically occurs in immunocompromised patients, although some vaccine strains of have been reported to cause invasive pneumococcal disease in immunocompetent vaccine recipients. In this study, we presented a case of a 16-month-old immunocompetent patient with lung abscess and empyema caused by nonvaccine serotype 24B. A consolidation occupying the right upper lobe in the chest computed tomography results, as observed at presentation, changed to thick-walled cavitary lesions at the end of a month of intravenous antibiotics, and antibiotics were continued for a total of two months. To the best of our knowledge this is the first report that focuses on the risk of invasive pneumococcal disease caused by serotype 24B in an immunocompetent child.
侵袭性肺炎球菌疾病通常发生在免疫功能低下的患者中，尽管有报道称一些疫苗株会在免疫功能正常的疫苗接种者中引起侵袭性肺炎球菌疾病。在本研究中，我们报告了一例16个月大免疫功能正常的患者，其因非疫苗血清型24B导致肺脓肿和脓胸。胸部计算机断层扫描结果显示，初诊时右上叶有实变影，静脉注射抗生素治疗一个月后变为厚壁空洞性病变，抗生素总共持续使用了两个月。据我们所知，这是第一份关注免疫功能正常儿童中由血清型24B引起的侵袭性肺炎球菌疾病风险的报告。
