National Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Huazhong Agricultural University, Wuhan 430070, China.
Guangxi Key Laboratory of Germplasm Innovation and Utilization of Specialty Commercial Crops in North Guangxi, Guangxi Academy of Specialty Crops, Guilin 541004, China.
Science. 2024 Feb 9;383(6683):659-666. doi: 10.1126/science.adl2953. Epub 2024 Feb 8.
Secretory structures in terrestrial plants serve as reservoirs for a variety of secondary metabolites. Among these, the secretory cavity of the Rutaceae family is notable for containing essential oils with a wide range of applications. However, the molecular basis underlying secretory cavity development is unknown. Here, we reveal a molecular framework for oil gland formation. Using genetic mapping and genome editing, we demonstrated that this process requires LATE MERISTEM IDENTITY1 (LMI1), a key regulator of leaf serration. A conserved GCC box element of the promoter recruits DORNROSCHEN-like (DRNL) for transcriptional activation. This cascade triggers activation, facilitating the development of oil glands and the biosynthesis of essential oils. Our findings spotlight -regulatory divergence within leaf shape genes, propelling novel functional tissue formation.
陆地植物的分泌结构作为各种次生代谢物的储库。在这些结构中，芸香科的分泌腔以含有广泛应用的精油而闻名。然而，分泌腔发育的分子基础尚不清楚。在这里，我们揭示了一个油脂腺形成的分子框架。使用遗传图谱和基因组编辑，我们证明这个过程需要 LATE MERISTEM IDENTITY1（LMI1），这是叶片锯齿的关键调节因子。 启动子的保守 GCC 盒元件招募 DORNROSCHEN-like（DRNL）进行转录激活。这个级联触发 激活，促进油腺的发育和精油的生物合成。我们的发现强调了叶片形状基因中的 -调控分歧，推动了新的功能组织形成。
