Giangrande A, Cantù P, Limido A, Allaria P, Brambilla Pisoni I
Blood Purif. 1985;3(4):187-91. doi: 10.1159/000169412.
Fluid overload is not infrequent in continuous ambulatory peritoneal dialysis (CAPD) patients. In our experience, extemporaneous continuous venous-venous hemofiltration (CVVHF) was able to correct fluid imbalances refractory to high dose diuretics and hypertonic solutions. We treated 8 of 52 patients (5 females, 3 males, mean age 52 years) on CAPD from 4 to 36 months and with fluid overloads of up to 10 kg. A Biospal SCU/CAVH flat-sheet high-flux hemodialyzer employed for 10 h produced an ultrafiltration rate (QB:150 ml/min) of 11.12 +/- 4.97 ml/min. With an isotonic replacement solution, the filter provided sufficient extraction of small molecules so that CAPD could be interrupted during CVVHF. The procedure appeared well tolerated. This approach reduced the use of hypertonic dialysate, which is not devoid of side effects on ultrafiltration capacity of the peritoneal membrane.
液体超负荷在持续性非卧床腹膜透析（CAPD）患者中并不少见。根据我们的经验，临时连续性静脉-静脉血液滤过（CVVHF）能够纠正对大剂量利尿剂和高渗溶液难治的液体失衡。我们对52例接受CAPD治疗4至36个月且液体超负荷达10千克的患者中的8例（5名女性，3名男性，平均年龄52岁）进行了治疗。使用Biospal SCU/CAVH平板高通量血液透析器进行10小时治疗，超滤率（QB：150毫升/分钟）为11.12±4.97毫升/分钟。使用等渗置换液时，该滤器能充分清除小分子物质，从而在CVVHF期间可中断CAPD。该操作耐受性良好。这种方法减少了高渗透析液的使用，而高渗透析液对腹膜超滤能力并非没有副作用。
