Thomson N M, Atkins R C, Humphery T J, Agar J M, Scott D F
Aust N Z J Med. 1983 Oct;13(5):489-96. doi: 10.1111/j.1445-5994.1983.tb02700.x.
This paper is a study of 117 patients with endstage renal failure, treated by continuous ambulatory peritoneal dialysis (CAPD) over periods of 1-56 months. The study has shown CAPD to be an effective form of dialysis with a number of advantages over intermittent peritoneal dialysis and hemodialysis (better control of salt and water status, hypertension and anemia, steady state biochemistry and greater ease of self-dialysis). Peritoneal clearance and ultrafiltration have remained adequate in all but a few patients. Hypoproteinemia, poor nutrition, obesity and abdominal herniae have been problems in a small percentage of patients. Hyperlipidemia has developed in half the patients but improved with diet. Peritonitis remains the major barrier to the more widespread use of CAPD, although its incidence can be considerably reduced by use of better connectors, bacterial filters and choice of patients.
本文对117例终末期肾衰竭患者进行了研究，这些患者接受持续非卧床腹膜透析（CAPD）治疗1至56个月。研究表明，CAPD是一种有效的透析方式，与间歇性腹膜透析和血液透析相比有诸多优势（能更好地控制盐和水的状态、高血压和贫血，生化指标稳定，且自我透析更简便）。除少数患者外，所有患者的腹膜清除率和超滤效果均保持良好。低蛋白血症、营养不良、肥胖和腹疝在一小部分患者中出现了问题。半数患者出现了高脂血症，但通过饮食调整有所改善。腹膜炎仍然是CAPD更广泛应用的主要障碍，不过使用更好的连接装置、细菌过滤器并选择合适的患者，其发生率可大幅降低。
