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沙特阿拉伯西北地区转诊医院弓形虫病的血清流行率。

Seroprevalence of toxoplasmosis at referral hospitals in the northwestern region, Saudi Arabia.

作者信息

Alharazi Talal, Alcantara Jerold C, Dando Lea L, Pangket Petelyne

机构信息

Department of Medical Laboratory Science, College of Applied Medical Science, University of Hail, Hail, Saudi Arabia.

Department of Medical Microbiology and Immunology, Faculty of Medicine and Health Sciences, Taiz University, Taiz, Yemen.

出版信息

J Educ Health Promot. 2023 Nov 27;12:391. doi: 10.4103/jehp.jehp_490_23. eCollection 2023.

Abstract

BACKGROUND

Toxoplasmosis is induced by , which affects 30 percent of the global population and is responsible for deaths related to foodborne pathogens. This study aimed to describe the seroprevalence of in patients attending referral hospitals in the northwestern region of Saudi Arabia.

MATERIALS AND METHODS

The serology test results for antibodies of 797 patients were retrospectively analyzed using the hospitals' database. The enzyme-linked immunosorbent assay was used to detect antibodies (IgG and/or IgM).

RESULTS

Overall, the prevalence of anti- antibodies was 8.3%. Higher (9.9%) prevalence of positive results among patients aged 30 years and above was observed. Statistically, the various age groups ( = 0.031) were found to be significant. Female was noted to have increased (8.1%) seroprevalence, and the incidence of infection occurred largely among participants living in rural areas (8.2%).

CONCLUSIONS

Toxoplasmosis remains a public health concern. The seroprevalence of antibodies was relatively low in the study area. IgG antibodies to were mainly detected. Increasing awareness on the mode of transmission, source of infection, and disease prevention through health education and dissemination is vital to reduce or eliminate toxoplasmosis.

摘要

背景

弓形虫病由[病原体名称未给出]引起,全球30%的人口受其影响,它是食源性病原体相关死亡的原因。本研究旨在描述沙特阿拉伯西北部转诊医院患者中[病原体名称未给出]的血清阳性率。

材料与方法

利用医院数据库对797例患者的[病原体名称未给出]抗体血清学检测结果进行回顾性分析。采用酶联免疫吸附试验检测[病原体名称未给出]抗体(IgG和/或IgM)。

结果

总体而言,抗[病原体名称未给出]抗体的患病率为8.3%。30岁及以上患者的阳性结果患病率较高(9.9%)。经统计学分析,发现各年龄组(P = 0.031)具有显著性差异。女性的血清阳性率有所增加(8.1%),感染发生率主要发生在农村地区的参与者中(8.2%)。

结论

弓形虫病仍然是一个公共卫生问题。研究区域内[病原体名称未给出]抗体的血清阳性率相对较低。主要检测到针对[病原体名称未给出]的IgG抗体。通过健康教育和宣传提高对传播方式、感染源和疾病预防的认识对于减少或消除弓形虫病至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f59/10852156/4105eb409d15/JEHP-12-391-g001.jpg

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