Alsaeed Ali, Alhaddad Mousa J, Alkhalifah Ridha H, Abu Shaigah Faisal A, Alshehab Manal M, Alali Zahra H, Ebrahim Sara H, Abdulla Hasan M, Al Ibraheem Ghadeer A, Al Bensaad Ghadeer A, Alaliw Welaa A, Alsheef Hawra J, Altriki Mohammed Y, Alkhalaf Abdullah A
Infectious Disease, Dammam Medical Complex, Dammam, SAU.
Internal Medicine, Dammam Medical Complex, Dammam, SAU.
Cureus. 2024 Jan 9;16(1):e51947. doi: 10.7759/cureus.51947. eCollection 2024 Jan.
Backgrounds People living with human immunodeficiency virus (HIV) are at a greater risk of chronic kidney disease (CKD) compared to people not having HIV. Evaluating the prevalence of CKD in people living with HIV in Dammam, Saudi Arabia was the main objective of this study. Methods This cross-sectional study included adult HIV patients who were followed at Dammam Medical Complex. The patients' demographic data, comorbid conditions, and HIV history were reviewed from their electronic medical records. Results A total of 729 patients were counted. The glomerular filtration rate (GFR) of 235 patients could not be estimated. The data for the remaining 494 patients were analyzed. The cohort consisted of 406 male patients (82.19%) and 88 female patients (17.81%). The mean ± standard deviation for the patients' age and HIV duration were 39.08±10.93 years and 4.37±3.15 years, respectively. Ten patients (2.02%) had a GFR of <60 mL/min/1.73 m. Among 136 patients who had an estimated GFR of ≥60 mL/min/1.73 m and were tested by a urine examination, 27 patients (19.85%) had albuminuria. Combining the two figures resulted in an estimated prevalence of CKD in HIV patients of 21.47%. Only one patient (0.02%) was receiving dialysis. Conclusions The prevalence of CKD in people living with HIV in Dammam, Saudi Arabia was higher than the general population. The findings highlight the elevated risk of CKD among people living with HIV and emphasize the importance of regular monitoring and early detection of kidney dysfunction in this population.
与未感染人类免疫缺陷病毒(HIV)的人群相比,HIV感染者患慢性肾脏病(CKD)的风险更高。本研究的主要目的是评估沙特阿拉伯达曼地区HIV感染者中CKD的患病率。方法:这项横断面研究纳入了在达曼医疗中心接受随访的成年HIV患者。从他们的电子病历中回顾了患者的人口统计学数据、合并症情况和HIV病史。结果:共统计了729例患者。235例患者的肾小球滤过率(GFR)无法估算。对其余494例患者的数据进行了分析。该队列包括406例男性患者(82.19%)和88例女性患者(17.81%)。患者年龄和HIV感染时长的平均值±标准差分别为39.08±10.93岁和4.37±3.15年。10例患者(2.02%)的GFR<60 mL/min/1.73 m²。在136例估算GFR≥60 mL/min/1.73 m²且接受了尿液检查的患者中,27例患者(19.85%)存在蛋白尿。将这两个数字相加得出HIV患者中CKD的估计患病率为21.47%。只有1例患者(0.02%)正在接受透析。结论:沙特阿拉伯达曼地区HIV感染者中CKD的患病率高于一般人群。研究结果凸显了HIV感染者中CKD风险的升高,并强调了对该人群定期监测和早期发现肾功能障碍的重要性。