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手术后心内脓肿分枝杆菌引起的软组织感染和骨髓炎:病例报告及文献复习

Soft tissue infection and osteomyelitis caused by Mycobacterium farcinogenes after heart surgery: Case report and literature review of human cases.

机构信息

Department of Pharmacy, The Second Affiliated Hospital of Army Medical University, Chongqing, China.

Department of Cardiac Surgery, The Second Affiliated Hospital of Army Medical University, Chongqing, China.

出版信息

Diagn Microbiol Infect Dis. 2024 Apr;108(4):116191. doi: 10.1016/j.diagmicrobio.2024.116191. Epub 2024 Jan 26.

DOI:10.1016/j.diagmicrobio.2024.116191
PMID:38335880
Abstract

Mycobacterium farcinogenes (M. farcinogenes) is rapidly growing mycobacterium, belonging to non-tuberculous mycobacterial (NTM). M. farcinogenes is an exceedingly rare causative agent of human infection. Only seven cases with M. farcinogenes infections in humans were reported. This is a case of soft tissue infection and osteomyelitis caused by M. farcinogenes after heart surgery. Microbial identification was achieved by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS). The clinical outcome was favorable after surgical debridement and 4-month antibiotics treatment. We also provide a comprehensive literature review on this disease.

摘要

化脓隐秘杆菌(M. farcinogenes)是一种快速生长的分枝杆菌,属于非结核分枝杆菌(NTM)。化脓隐秘杆菌是人感染的一种极为罕见的病原体。仅有 7 例人类化脓隐秘杆菌感染的报道。这是心脏手术后化脓隐秘杆菌引起的软组织感染和骨髓炎。微生物鉴定通过基质辅助激光解吸/电离飞行时间质谱(MALDI-TOF-MS)完成。经手术清创和 4 个月的抗生素治疗后,临床结果良好。我们还对该病进行了全面的文献复习。

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