Kashihara Eriko, Fujita Kohei, Yamamoto Hiroshi, Odagaki Takao
Department of Infectious Diseases, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
Department of General Internal Medicine, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
IDCases. 2022 Mar 7;28:e01468. doi: 10.1016/j.idcr.2022.e01468. eCollection 2022.
is the causative agent of bovine farcy. shares common properties with rapidly growing mycobacteria, and distinguishing between and is reportedly complex and challenging. Moreover, few studies have isolated from human clinical samples. A previously healthy 37-year-old male construction worker presented to the emergency department after a severe injury and was diagnosed with a Gustilo-Anderson type ⅢA fracture. After an uneventful postoperative period of two months, he experienced pain and serous discharge from the upper shin and lower calf region. Frequent debridement provided no relief, and the pathology cultures of the tissue were negative. However, was isolated from the fluid of the wound. The patient's symptoms gradually improved with anti-mycobacterial drug treatment. Nontuberculous mycobacterial infections, including those caused by , should be considered in patients developing soft tissue infections despite negative pyogenic bacterial cultures several months after sustaining an open fracture.
是牛皮肤鼻疽的病原体。它与快速生长的分枝杆菌具有共同特性，据报道区分和很复杂且具有挑战性。此外，很少有研究从人类临床样本中分离出。一名先前健康的37岁男性建筑工人在遭受严重损伤后到急诊科就诊，被诊断为 Gustilo-AndersonⅢA型骨折。经过两个月平稳的术后恢复，他的胫骨上段和小腿下段出现疼痛和浆液性分泌物。频繁清创未能缓解症状，组织病理培养结果为阴性。然而，从伤口液体中分离出了。抗分枝杆菌药物治疗后患者症状逐渐改善。对于开放性骨折数月后发生软组织感染且化脓性细菌培养结果为阴性的患者，应考虑非结核分枝杆菌感染，包括由引起的感染。
