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超重/肥胖与正常体重儿童在 6 分钟步行试验(6MWT)中的表现比较及其与血液动力学参数的关系:四所小学的横断面研究。

Comparison of Performance in the Six-Minute Walk Test (6MWT) between Overweight/Obese and Normal-Weight Children and Association with Haemodynamic Parameters: A Cross-Sectional Study in Four Primary Schools.

机构信息

Department of Medicine, University of Verona, 37100 Verona, Italy.

Department of Surgical, Odontostomatological and Maternal-Infantile Sciences, University of Verona, 37129 Verona, Italy.

出版信息

Nutrients. 2024 Jan 25;16(3):356. doi: 10.3390/nu16030356.

Abstract

Physical activity plays a pivotal role in preventing obesity and cardiovascular risks. The six-minute walk test (6MWT) is a tool to assess functional capacity and predict cardiovascular events. The aim of this cross-sectional study was to compare the performance and haemodynamic parameters before and after a 6MWT between obese/overweight vs. normal-weight children (average age 8.7 ± 0.7 years) participating in a project involving four primary schools in South Verona (Italy). Validated questionnaires for physical activity and diet, as well as blood drops, were collected. Overweight or obese children (OW&OB; = 100) covered a shorter 6MWT distance compared to normal-weight children (NW, = 194). At the test's conclusion, the OW&OB group exhibited a higher Rate Pulse Product (RPP = Systolic Blood Pressure × Heart Rate) as compared to the NW. Body Mass Index, waist-to-height ratio, fat mass by electrical impedance, and trans fatty acids showed direct correlations with pre and post-test haemodynamic parameters, such as RPP, and inverse correlations with oxygen saturation. OW&OB children demonstrated lower performance in this low-intensity exercise test, along with an elevated haemodynamic response. Excess fat in childhood can be considered a risk factor for haemodynamic stress, with potential deleterious consequences later in life. Efforts should be initiated early to break this cycle.

摘要

身体活动在预防肥胖和心血管风险方面起着关键作用。六分钟步行测试(6MWT)是评估功能能力和预测心血管事件的工具。本横断面研究的目的是比较肥胖/超重与正常体重儿童(平均年龄 8.7 ± 0.7 岁)在参加涉及意大利南维罗纳四所小学的项目前后的表现和血液动力学参数。收集了经过验证的身体活动和饮食问卷,以及血滴。与正常体重儿童(NW,n = 194)相比,超重或肥胖儿童(OW&OB,n = 100)在 6MWT 中覆盖的距离更短。在测试结束时,OW&OB 组的心率乘积(RPP = 收缩压×心率)高于 NW。体重指数、腰高比、电阻抗法测定的脂肪量和反式脂肪酸与前后测试的血液动力学参数(如 RPP)呈直接相关,与血氧饱和度呈负相关。OW&OB 儿童在这项低强度运动测试中的表现较差,同时血液动力学反应增强。儿童时期的多余脂肪可被视为血液动力学应激的一个危险因素,可能对以后的生活产生有害影响。应尽早开始努力打破这种循环。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5335/10857357/3cadb5d9e269/nutrients-16-00356-g001.jpg

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