Department of Translational Medicine and Surgery, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Pediatric Gastroenterology and Liver Unit, Sapienza University of Rome, Umberto I Hospital, 00161 Rome, Italy.
Nutrients. 2024 Jan 30;16(3):400. doi: 10.3390/nu16030400.
The infant gut microbiome plays a key role in the healthy development of the human organism and appears to be influenced by dietary practices through multiple pathways. First, maternal diet during pregnancy and infant nutrition significantly influence the infant gut microbiota. Moreover, breastfeeding fosters the proliferation of beneficial bacteria, while formula feeding increases microbial diversity. The timing of introducing solid foods also influences gut microbiota composition. In preterm infants the gut microbiota development is influenced by multiple factors, including the time since birth and the intake of breast milk, and interventions such as probiotics and prebiotics supplementation show promising results in reducing morbidity and mortality in this population. These findings underscore the need for future research to understand the long-term health impacts of these interventions and for further strategies to enrich the gut microbiome of formula-fed and preterm infants.
婴儿肠道微生物群在人类机体的健康发育中起着关键作用,并且似乎通过多种途径受到饮食实践的影响。首先,孕妇在怀孕期间的饮食和婴儿营养显著影响婴儿肠道微生物群。此外,母乳喂养促进有益细菌的增殖,而配方奶喂养则增加微生物多样性。引入固体食物的时间也会影响肠道微生物群的组成。在早产儿中,肠道微生物群的发育受到多种因素的影响,包括出生后的时间、母乳的摄入以及益生菌和益生元等干预措施的补充,这些干预措施在降低该人群的发病率和死亡率方面显示出有前景的结果。这些发现强调了未来研究的必要性,以了解这些干预措施的长期健康影响,并制定进一步的策略来丰富配方喂养和早产儿的肠道微生物群。
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