Department of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 1st Decembrie Street, 410073 Oradea, Romania.
Faculty of Pharmacy, "Iuliu Hatieganu" University of Medicine and Pharmacy, 8 Victor Babes Street, 400012 Cluj-Napoca, Romania.
Molecules. 2024 Jan 27;29(3):608. doi: 10.3390/molecules29030608.
The status of parsley as a well-known folk medicine noted for its nutritional and medicinal properties prompted the exploration of its potential as a functional food and natural remedy. The paper aims to investigate the potential of parsley to enhance muscle function and alleviate psoriasiform dermatitis, eventually establishing it as a natural, well-tolerated alternative with specific benefits for both muscles and skin. This study examines the tolerability of parsley in a cohort of 937 participants by assessing immunoglobulin G (IgG) reactions. The findings reveal high tolerability, as 96.26% of participants experienced no adverse effects. Among the 902 individuals lacking hypersensitivity, 37.02% reported muscle cramps, with a notable 15.02% reduction observed in the subgroup consuming parsley juice. In the subset of 32 subjects with dermatitis, the application of parsley extract ointment led to a significant decrease in dermatological parameters (redness, thickness, scaling). While the control group exhibited improvements, statistical significance was not observed. Notably, four categories of affected area reduction were identified, with scaling demonstrating the most pronounced impact. The results propose that parsley holds promise for favorable tolerability, contributing to the alleviation of muscle cramps and presenting an effective alternative in dermatitis treatment. Nonetheless, sustained validation through long-term studies is imperative to substantiate these preliminary findings.
欧芹作为一种具有营养和药用特性的知名民间药物，其地位促使人们探索其作为功能性食品和天然疗法的潜力。本文旨在研究欧芹增强肌肉功能和缓解银屑病样皮炎的潜力，最终将其确立为一种天然、耐受性良好的替代方法，对肌肉和皮肤均具有特定益处。本研究通过评估免疫球蛋白 G（IgG）反应，调查了欧芹在 937 名参与者中的耐受性。研究结果显示，欧芹具有很高的耐受性，因为 96.26%的参与者没有出现不良反应。在 902 名没有过敏反应的人中，有 37.02%的人报告有肌肉痉挛，而饮用欧芹汁的亚组痉挛发生率显著降低了 15.02%。在 32 名患有皮炎的受试者亚组中，使用欧芹提取物软膏可显著降低皮肤参数（红斑、厚度、鳞屑）。对照组虽有改善，但未观察到统计学意义。值得注意的是，发现了四类受影响面积减少的情况，其中鳞屑减少最为明显。结果表明，欧芹具有良好的耐受性，有望缓解肌肉痉挛，并为皮炎治疗提供有效替代方案。然而，需要通过长期研究进行持续验证，以证实这些初步发现。
