Coran A G, Jordan F T, Wesley J R
Int Surg. 1985 Oct-Dec;70(4):335-7.
The standard surgical approach to multiple polyposis has been a total proctocolectomy and an end ileostomy because of the premalignant nature of the disease. This operation has been successful, but has resulted in a significant amount of psychological trauma due to the presence of an abdominal stoma. For that reason, we have utilized the sphincter-saving operation, namely, the endorectal pull-through for the definitive management of patients with familial polyposis since 1979. During the years 1979 to 1984, seven patients (4 female and 3 male), ranging in age from 10 to 30 years, have undergone an endorectal pull-through at our institution. Four of these patients had previously undergone a subtotal colectomy and ileoproctostomy and were seen because of persistent polyps in the remaining rectum. The operation consisted of a total colectomy, a mucosal proctectomy, an ileoanostomy and a loop ileostomy (1 patient did not undergo a loop ileostomy). The loop ileostomy was closed about two months after the pull-through procedure. There was no mortality and only one complication was seen postoperatively. This complication consisted of a bowel obstruction one week after ileostomy closure which was successfully treated with an enterolysis. Patient satisfaction has been excellent. All patients have either returned to full-time work or full-time school activity. All were completely continent immediately after ileostomy closure, both during the day and at night. The median stool frequency one year after the operation is five stools per 24 hours. Our results with this operation have encouraged us to recommend the endorectal pull-through to all patients with multiple polyposis.
由于该病具有癌前病变的性质,针对多发性息肉病的标准手术方法一直是全直肠结肠切除术和末端回肠造口术。该手术已取得成功,但由于腹部造口的存在,导致了大量的心理创伤。因此,自1979年以来,我们采用了保留括约肌的手术,即直肠内拖出术来确定性治疗家族性息肉病患者。在1979年至1984年期间,7例患者(4例女性和3例男性),年龄在10至30岁之间,在我们机构接受了直肠内拖出术。其中4例患者此前接受了结肠次全切除术和回肠直肠吻合术,因剩余直肠中持续存在息肉而前来就诊。手术包括全结肠切除术、直肠黏膜切除术、回肠肛门吻合术和袢式回肠造口术(1例患者未进行袢式回肠造口术)。在拖出术后约两个月关闭袢式回肠造口。无死亡病例,术后仅出现1例并发症。该并发症为回肠造口关闭一周后发生的肠梗阻,经肠粘连松解术成功治疗。患者满意度极佳。所有患者均已恢复全职工作或全职学校活动。回肠造口关闭后,所有患者立即白天和夜间均完全能自主控制排便。术后一年大便频率中位数为每24小时5次。我们的手术结果促使我们向所有多发性息肉病患者推荐直肠内拖出术。