Türkoğlu Gizem Ceylan, Khomarloo Niloufar, Mohsenzadeh Elham, Gospodinova Dilyana Nikolaeva, Neznakomova Margarita, Salaün Fabien
Department of Textile Engineering, Dokuz Eylul University, İzmir 35397, Turkey.
Univ. Lille, ENSAIT, ULR 2461-GEMTEX-Génie et Matériaux Textiles, F-59000 Lille, France.
Int J Mol Sci. 2024 Jan 30;25(3):1668. doi: 10.3390/ijms25031668.
Poly(vinyl alcohol) is one of the most attractive polymers with a wide range of uses because of its water solubility, biocompatibility, low toxicity, good mechanical properties, and relatively low cost. This review article focuses on recent advances in poly(vinyl alcohol) electrospinning and summarizes parameters of the process (voltage, distance, flow rate, and collector), solution (molecular weight and concentration), and ambient (humidity and temperature) in order to comprehend the influence on the structural, mechanical, and chemical properties of poly(vinyl alcohol)-based electrospun matrices. The importance of poly(vinyl alcohol) electrospinning in biomedical applications is emphasized by exploring a literature review on biomedical applications including wound dressings, drug delivery, tissue engineering, and biosensors. The study also highlights a new promising area of particles formation through the electrospraying of poly(vinyl alcohol). The limitations and advantages of working with different poly(vinyl alcohol) matrices are reviewed, and some recommendations for the future are made to advance this field of study.
聚乙烯醇是最具吸引力的聚合物之一,因其具有水溶性、生物相容性、低毒性、良好的机械性能以及相对较低的成本而有着广泛的用途。这篇综述文章聚焦于聚乙烯醇静电纺丝的最新进展,并总结了该过程的参数(电压、距离、流速和收集器)、溶液参数(分子量和浓度)以及环境参数(湿度和温度),以便了解它们对基于聚乙烯醇的静电纺丝基质的结构、机械和化学性质的影响。通过对包括伤口敷料、药物递送、组织工程和生物传感器在内的生物医学应用进行文献综述,强调了聚乙烯醇静电纺丝在生物医学应用中的重要性。该研究还突出了通过聚乙烯醇电喷雾形成颗粒这一充满前景的新领域。综述了使用不同聚乙烯醇基质的局限性和优势,并对该研究领域的未来发展提出了一些建议。