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结肠切除术后10年发生的肝门附近结直肠癌肝转移的中央肝切除术的雷纳克氏入路:病例报告

Laennec's approach for central liver resection of colorectal cancer liver metastasis adjacent to the hepatic hilum that occurred 10 years after colectomy: A case report.

作者信息

Burlaka Anton, Rozhkova Veronika, Pavliuk Romanna, Chukanov Oleksandr, Beznosenko Andriy

机构信息

Department of thoraco-abdominal oncology, National Cancer Institute, Kyiv, Ukraine.

Department of thoraco-abdominal oncology, National Cancer Institute, Kyiv, Ukraine.

出版信息

Int J Surg Case Rep. 2024 Mar;116:109327. doi: 10.1016/j.ijscr.2024.109327. Epub 2024 Feb 1.

DOI:10.1016/j.ijscr.2024.109327
PMID:38340620
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10943644/
Abstract

INTRODUCTION AND IMPORTANCE

Colorectal cancer ranks as one of the most common cancer globally. About half of the patients experience a disease recurrence in the form of сolorectal cancer liver metastasis (CRLM) within the first 5 years of the course of the disease. However, there are rare cases of delayed onset of liver metastasis, that occur after cessation of standard follow-up.

CASE PRESENTATION

A 38-year-old woman was referred to our institute with a metastatic liver mass adjacent to the liver hilum. The patient had sigmoid colectomy 10 years ago. After 6 cycles of chemotherapy, she underwent a central liver resection: Sg4, Sg5, Sg8v + middle hepatic vein with surgical skeletonization of 1st and 2nd order hepatic pedicles. The patient was discharged on 5th post-operative day. After 18th month of follow-up, the patient was alive without any signs of recurrence.

CLINICAL DISCUSSION

The recommended follow-up of colorectal cancer patients is 5 years. However, there are rare instances of late metachronous liver recurrences, that suggest the necessity of more continuous surveillance. For patients with CRLM surgical resection is considered the most radical treatment of choice. The anatomy of Laennec's capsule allows the precise isolation of hepatic pedicles and can facilitate anatomical hepatectomy.

CONCLUSION

We present a rare case report of borderline-resectable CRLM successfully treated with central liver resection with application of Laennec's approach a decade after the resection of a primary colorectal tumor.

摘要

引言与重要性

结直肠癌是全球最常见的癌症之一。约一半的患者在疾病进程的前5年内会以结直肠癌肝转移(CRLM)的形式出现疾病复发。然而,也有罕见的肝转移延迟发生的情况,即在标准随访结束后出现。

病例介绍

一名38岁女性因肝门附近的转移性肝肿块被转诊至我院。该患者10年前接受了乙状结肠切除术。经过6个周期的化疗后,她接受了中央肝切除术:切除Sg4、Sg5、Sg8v以及肝中静脉,并对第一和第二级肝蒂进行手术骨骼化处理。患者术后第5天出院。随访18个月后,患者存活且无任何复发迹象。

临床讨论

结直肠癌患者推荐的随访时间为5年。然而,存在罕见的晚期异时性肝复发情况,这表明需要进行更持续的监测。对于CRLM患者,手术切除被认为是最彻底的治疗选择。赖内克囊的解剖结构允许精确分离肝蒂,并有助于进行解剖性肝切除术。

结论

我们报告了一例罕见的边缘可切除CRLM病例,在原发性结直肠肿瘤切除十年后,应用赖内克方法成功进行中央肝切除治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b9c/10943644/3d2ecc6d725d/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b9c/10943644/3219d9237473/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b9c/10943644/4db85561b863/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b9c/10943644/09fb25146970/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b9c/10943644/3d2ecc6d725d/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b9c/10943644/3219d9237473/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b9c/10943644/4db85561b863/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b9c/10943644/09fb25146970/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b9c/10943644/3d2ecc6d725d/gr4.jpg

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