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雅致樟 Ocotea indecora (Schott) Mez 精油纳米乳剂在血吸虫病防治中的潜力:杀螺效果

Potential of Ocotea indecora (Schott) Mez essential oil nanoemulsion in schistosomiasis control: Molluscicidal effects.

作者信息

Paiva Machado Francisco, da Silva Rangel Leonardo, Nunes Farias Gomes Keyla, Albuquerque Dos Santos José Augusto, Xavier Faria Robson, Santos Marcelo G, Fernandes Caio P, Rocha Leandro

机构信息

Laboratório de Tecnologia de Produtos Naturais, Departamento de Tecnologia Farmacêutica, Faculdade de Farmácia, Universidade Federal Fluminense, Rua Dr Mario Viana 523, CEP 24241-000, Santa Rosa, Niterói, Rio de Janeiro, Brazil; Departamento de Farmácia e Administração Farmacêutica, Universidade Federal Fluminense, Rua Dr. Mario Viana 523, CEP 24241-000, Santa Rosa, Niterói, Rio de Janeiro, Brazil.

Laboratório de Avaliação e Promoção da Saúde Ambiental, Instituto Oswaldo Cruz, CEP 21040360, Rio de Janeiro, Brazil.

出版信息

Exp Parasitol. 2024 Apr;259:108717. doi: 10.1016/j.exppara.2024.108717. Epub 2024 Feb 9.

Abstract

Schistosomiasis is a neglected disease transmitted through contaminated water in populations with low basic sanitation. The World Health Organization recommends controlling the intermediate host snails of the Biomphalaria genus with the molluscicide niclosamide. This work aims to evaluate the biocidal potential of the nanoemulsion prepared with the essential oil of Ocotea indecora leaves for the control of the mollusk Biomphalaria glabrata, intermediate host of the Schistosoma mansoni, the etiologic agent of schistosomiasis.

摘要

血吸虫病是一种被忽视的疾病,在基本卫生条件差的人群中通过受污染的水传播。世界卫生组织建议使用杀螺剂氯硝柳胺来控制双脐螺属的中间宿主螺类。这项工作旨在评估用奥氏樟树叶精油制备的纳米乳剂对曼氏血吸虫病病原体曼氏血吸虫的中间宿主光滑双脐螺的杀灭潜力。

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