Department of Orthopedic Oncology Surgery, Beijing Ji Shui Tan Hospital, Peking University, Beijing, People's Republic of China.
Sci Rep. 2024 Feb 10;14(1):3412. doi: 10.1038/s41598-024-52019-1.
To evaluate whether single acetabular column can be reserved and the effect of reconstruction with femoral head plus total hip replacement (THR) for primary malignant peri-acetabulum tumors. From 2007 to 2015, nineteen patients with primary malignant peri-acetabulum tumors were enrolled. All cases underwent single column resection with clear surgical margins. Ten of the 19 tumor's resections were assisted by computer navigation. Femoral heads were applied to reconstruct anterior or posterior column defects; THR was used for joint reconstruction. The surgical safety, oncologic outcome and prosthesis survivorship and function were evaluated by regular follow-up. The average follow-up period was 65.9 months. Surgical margins contained wide resection in 12 cases and marginal resection in 7 cases. One patient with Ewing's sarcoma died 14 months postoperative due to lung metastasis. One case with chondrosarcoma had recurrence. One prosthesis was removed due to infection. The average MusculoSkeletal Tumor Society (MSTS) function score was 83.7%. Due to the relative small number of cases, there was no significant difference in the recurrence rate and prosthesis failure rate between the navigation group and non-navigation group. Single column resection and reconstruction with femoral head autograft plus THR is an effective, safe method with less complication rate and better functional outcome for patients with peri-acetabular tumors.
为了评估是否可以保留单个髋臼柱,并探讨在原发性恶性髋臼周围肿瘤中采用股骨头加全髋关节置换术(THR)进行重建的效果。2007 年至 2015 年,共纳入 19 例原发性恶性髋臼周围肿瘤患者。所有病例均行单一柱切除,保证手术切缘清晰。其中 10 例肿瘤切除采用计算机导航辅助。采用股骨头重建前柱或后柱缺损,行 THR 关节重建。通过定期随访评估手术安全性、肿瘤学结果以及假体的存活率和功能。平均随访时间为 65.9 个月。手术切缘包含广泛切除 12 例,边缘切除 7 例。1 例尤文肉瘤患者术后 14 个月因肺转移死亡,1 例软骨肉瘤患者复发,1 例因感染而取出假体。平均肌骨肿瘤学会(MSTS)功能评分为 83.7%。由于病例数量相对较少,导航组和非导航组之间的复发率和假体失败率无显著差异。对于髋臼周围肿瘤患者,采用股骨头自体移植加 THR 的单一柱切除和重建是一种有效、安全的方法,并发症发生率较低,功能结果较好。