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髋臼周围肿瘤切除术后鞍状假体的长期临床效果不佳。

Poor long-term clinical results of saddle prosthesis after resection of periacetabular tumors.

机构信息

Department of Orthopaedics & Trauma, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands.

出版信息

Clin Orthop Relat Res. 2013 Jan;471(1):324-31. doi: 10.1007/s11999-012-2631-x. Epub 2012 Oct 5.

Abstract

BACKGROUND

The saddle prosthesis originally was developed to reconstruct large acetabular defects in revision hip arthroplasty and was used primarily for hip reconstruction after periacetabular tumor resections. The long-term survival of these reconstructions is unclear.

QUESTIONS/PURPOSE: We therefore examined the long-term function, complications, and survival in patients treated with saddle prostheses after periacetabular tumor resection.

PATIENTS AND METHODS

Between 1987 and 2003 we treated 17 patients with a saddle prosthesis after periacetabular tumor resection (12 chondrosarcomas, three osteosarcomas, one malignant fibrous histiocytoma, one metastasis). During followup, 11 patients died, resulting in a median overall survival of 49 months (95% CI, 30-68 months). The remaining six patients were alive without disease (mean followup, 12.1 years; range, 8.3-16.8 years). In one patient the saddle prosthesis was removed after 3 months owing to dislocation and infection. We obtained SF-36 questionnaires, Toronto Extremity Salvage Scores (TESS), and Musculoskeletal Tumor Society (MSTS) scores.

RESULTS

Thirteen of 17 patients used walking assists for mobilization at last followup: eight patients required two crutches, five needed one crutch, and one did not use any walking aids. The other three patients were not able to mobilize independently and only made bed to chair transfers. The mean hip flexion in the six surviving patients was 60° (range, 40°-100°) at last followup. Local complications were seen in 14 of the 17 patients: nine wound infections, seven dislocations, and two leg-length discrepancies requiring additional surgery. In the five surviving patients with their index prosthesis still in situ, the mean MSTS score at long-term followup was 47% (range, 20%-77%), the mean TESS score was 53% (range, 41%-67%), and the mean composite SF-36 physical and mental component summaries were 43.9 and 50.6, respectively.

CONCLUSION

Reconstruction with saddle prostheses after periacetabular tumor surgery has a high risk of complications and poor long-term function with limited hip flexion; therefore, we no longer use the saddle prosthesis for reconstruction after periacetabular tumor resections.

摘要

背景

鞍状假体最初是为了重建髋关节翻修术中的大髋臼缺损而开发的,主要用于髋臼周围肿瘤切除后的髋关节重建。这些重建的长期生存率尚不清楚。

问题/目的:因此,我们检查了髋臼周围肿瘤切除后使用鞍状假体治疗的患者的长期功能、并发症和生存率。

患者和方法

1987 年至 2003 年,我们对 17 例髋臼周围肿瘤切除后使用鞍状假体的患者进行了治疗(12 例软骨肉瘤、3 例骨肉瘤、1 例恶性纤维组织细胞瘤、1 例转移瘤)。随访期间,11 例患者死亡,总生存率中位数为 49 个月(95%CI,30-68 个月)。其余 6 例患者无疾病存活(平均随访 12.1 年;范围,8.3-16.8 年)。1 例患者因脱位和感染在 3 个月后取出鞍状假体。我们获得了 SF-36 问卷、多伦多四肢挽救评分(TESS)和肌肉骨骼肿瘤学会(MSTS)评分。

结果

17 例患者中有 13 例在最后一次随访时使用助行器移动:8 例需要双拐,5 例需要单拐,1 例不需要任何助行器。另外 3 名患者无法独立移动,只能从床上转移到椅子上。6 例存活患者的平均髋关节屈曲度为 60°(范围,40°-100°)。17 例患者中有 14 例出现局部并发症:9 例伤口感染,7 例脱位,2 例肢体长度差异需要额外手术。在 5 例存活患者中,其指数假体仍在位,长期随访的平均 MSTS 评分为 47%(范围,20%-77%),平均 TESS 评分为 53%(范围,41%-67%),平均综合 SF-36 身体和精神成分综合评分为 43.9 和 50.6。

结论

髋臼周围肿瘤手术后使用鞍状假体重建具有很高的并发症风险和较差的长期功能,髋关节屈曲度有限;因此,我们不再使用鞍状假体进行髋臼周围肿瘤切除后的重建。

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