Suppr超能文献

沙特阿拉伯王国 EQ-5D-5L 的评估:一项全国代表性研究。

Valuation of EQ-5D-5L in the Kingdom of Saudi Arabia: A National Representative Study.

机构信息

Alfaisal University Alfaisal University, Colleges of Medicine and Pharmacy, Riyadh, Saudi Arabia; Therapeutics Affairs, Ministry of Health, Riyadh, Saudi Arabia.

Drug Policy and Regulation Department, Ministry of Health, Riyadh, Saudi Arabia.

出版信息

Value Health. 2024 May;27(5):552-561. doi: 10.1016/j.jval.2024.01.017. Epub 2024 Feb 9.

Abstract

OBJECTIVES

To estimate a Saudi-specific value set for the EQ-5D-5L questionnaire using the EuroQol Valuation Technology program and the EuroQol Group's standard protocol.

METHODS

Participants were quota-sampled from the Saudi adult population based on residency location, age group, gender, education level, and employment status. The participants were guided through the completion of composite time trade-off (cTTO) and discrete choice experiment (DCE) tasks by trained interviewers using EuroQol Valuation Technology software. Quality control (QC) measures were used to ensure good data quality. Random intercept and Tobit models analyzed the cTTO data, as well as models correcting for heteroskedasticity. DCE data were analyzed using conditional logit models, whereas hybrid models were used to analyze the cTTO and DCE data jointly. To evaluate model performance, prediction accuracy, logical consistency, significance level, and goodness of fit were used.

RESULTS

The valuation study included a representative sample of the Saudi population (N = 1000). The hybrid heteroskedastic model without a constant was chosen as the preferred model for generating the value set. The predicted values ranged from -0.683 for the worst health state ("55555") to 1 for the full health state ("11111"). Pain and discomfort had the largest impact on health-state preference values, whereas usual activities had the least.

CONCLUSION

The value set for the Kingdom of Saudi Arabia is the first value set for the EQ-5D-5L for any country in the Middle East. The value set can be used in Saudi health system economic evaluations and decision making.

摘要

目的

使用 EuroQol 估值技术程序和 EuroQol 集团的标准协议,估算沙特特定的 EQ-5D-5L 问卷值集。

方法

根据居住地点、年龄组、性别、教育水平和就业状况,从沙特成年人群中按配额抽样参与者。受过培训的访谈者使用 EuroQol 估值技术软件指导参与者完成综合时间权衡 (cTTO) 和离散选择实验 (DCE) 任务。使用质量控制 (QC) 措施确保数据质量良好。随机截距和 Tobit 模型分析了 cTTO 数据,以及纠正异方差的模型。使用条件逻辑回归模型分析了 DCE 数据,而混合模型则用于联合分析 cTTO 和 DCE 数据。为了评估模型性能,使用了预测准确性、逻辑一致性、显著性水平和拟合优度。

结果

这项估值研究包括了沙特代表性人口的样本(N=1000)。选择没有常数的混合异方差模型作为生成值集的首选模型。预测值的范围从最差健康状态(“55555”)的-0.683 到完全健康状态(“11111”)的 1。疼痛和不适对健康状态偏好值的影响最大,而通常的活动影响最小。

结论

沙特王国的价值集是中东任何国家 EQ-5D-5L 的第一个价值集。该价值集可用于沙特卫生系统的经济评估和决策。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验