Garratt Andrew M, Stavem Knut, Shaw James W, Rand Kim
Division for Health Services, Norwegian Institute of Public Health, Oslo, Norway.
Health Services Research Unit, Akershus University Hospital, Nordbyhagen, Norway.
Qual Life Res. 2025 Feb;34(2):417-427. doi: 10.1007/s11136-024-03837-3. Epub 2024 Nov 20.
To develop the Norwegian value set for the EQ-5D-5L based on interviews with a representative sample of the Norwegian adult population.
Random and quota sampling were used to recruit the sample of adults (age> 18 years) representative of the Norwegian general population. Data collection followed EQ-VT 2.1 undertaken before and after the COVID-19 pandemic from November 2019 to December 2022, using PC-assisted and video conferencing interviews, respectively. Each respondent valued 10 health states using composite time trade-off (cTTO) and 7 health states using a discrete choice experiment (DCE). Different statistical models were assessed for logical consistency and predictive accuracy using cTTO and DCE data alone or in combination as hybrid models.
Of the 1,321 respondents, 1,237 met inclusion criteria. All statistical models demonstrated logical consistency. The weighted hybrid model combining both cTTOand DCE data was preferred and had the highest predictive accuracy. Predicted values ranged from -0.453 to 1, and the dimension of anxiety/depression was the most highly valued by respondents, followed by pain/discomfort, self-care, mobility, and usual activities. These findings are not dissimilar to those for most Western European countries, and regression coefficients are closest to those for other Scandinavian countries.
This study provides the Norwegian value set for the EQ-5D-5L based on health state values obtained from members of the adult general population in Norway. This is an important contribution to economic evaluation and the broader application ofthe EQ-5D-5L in Norway including clinical and health services research, and quality measurement.
基于对挪威成年人群代表性样本的访谈，制定挪威版EQ-5D-5L价值集。
采用随机抽样和配额抽样的方法招募代表挪威普通人群的成年人样本（年龄>18岁）。分别于2019年11月至2022年12月在新冠疫情前后按照EQ-VT 2.1进行数据收集，分别采用电脑辅助访谈和视频会议访谈。每位受访者使用综合时间权衡法（cTTO）对10种健康状态进行估值，使用离散选择实验（DCE）对7种健康状态进行估值。单独使用cTTO和DCE数据或作为混合模型结合使用，评估不同统计模型的逻辑一致性和预测准确性。
在1321名受访者中，1237名符合纳入标准。所有统计模型均显示出逻辑一致性。结合cTTO和DCE数据的加权混合模型更受青睐，且预测准确性最高。预测值范围为-0.453至1，焦虑/抑郁维度是受访者最看重的，其次是疼痛/不适、自我护理、活动能力和日常活动。这些结果与大多数西欧国家的结果并无不同，回归系数与其他斯堪的纳维亚国家最接近。
本研究基于从挪威成年普通人群成员获得的健康状态值，提供了挪威版EQ-5D-5L价值集。这对挪威的经济评估以及EQ-5D-5L在包括临床和卫生服务研究以及质量测量在内的更广泛应用做出了重要贡献。
