Tabiti Hajar, Guensi Amal, Bendahhou Karima
Laboratory of Cellular and Molecular Pathophysiology of Inflammation, Degeneration, and Oncology, Hassan II University of Casablanca, Casablanca, MAR.
Department of Nuclear Medicine, Ibn Rochd Hospital, Casablanca, MAR.
Cureus. 2024 Jan 10;16(1):e52033. doi: 10.7759/cureus.52033. eCollection 2024 Jan.
Thyroid carcinoma (TC) represents the most frequent type of endocrine cancers, with its incidence steadily increasing worldwide. Our study aimed to describe the epidemiological and histological characteristics of differentiated thyroid carcinoma (DTC) at the Department of Nuclear Medicine in Ibn Rochd University Hospital, Casablanca, Morocco.
This was a cross-sectional study of DTC cases treated between 2004 and 2012 in the Department of Nuclear Medicine at Ibn Rochd University Hospital. We retrospectively reviewed medical records at this department, focusing on sociodemographic characteristics, such as age, gender, geographic origin, family history of cancer, and clinical information related to tumor features, including histological type, tumor size, and multifocality. The data were statistically analyzed using the jamovi 2.3.17 software (released September 2022, the jamovi project, retrieved from https://www.jamovi.org), considering the characteristics of the variables.
The findings revealed that 89% of the patients were females, and 78.7% were under the age of 55, ranging from 14 to 85 years. Married status represented 75.25% of our cases. Personal history of cancer and a family history of thyroid carcinoma were present in 0.9% and 1.17%, respectively. Concerning histological characteristics, the main histological type was papillary thyroid carcinoma (PTC) at 93%. Within these 1,283 cases, the follicular variant was the most frequent (42.89%). In addition, the tumor size was less than 2 cm in 43.80%, and it was encapsulated in 21.60%. Moreover, we staged our data according to the 8th edition of the American Joint Committee on Cancer staging system, revealing that at the time of diagnosis, 94.13% were in stage I.
This study provides an overview of the epidemiological and histological characteristics of DTC in Morocco. The findings highlight the diversity and differences between clinical presentation and epidemiological profile in Moroccan patients, contributing to a better understanding of the disease and facilitating adapted management.
甲状腺癌（TC）是最常见的内分泌癌症类型，其发病率在全球范围内稳步上升。我们的研究旨在描述摩洛哥卡萨布兰卡伊本·罗什德大学医院核医学科分化型甲状腺癌（DTC）的流行病学和组织学特征。
这是一项对2004年至2012年期间在伊本·罗什德大学医院核医学科接受治疗的DTC病例的横断面研究。我们回顾性地查阅了该科室的病历，重点关注社会人口学特征，如年龄、性别、地理来源、癌症家族史，以及与肿瘤特征相关的临床信息，包括组织学类型、肿瘤大小和多灶性。考虑到变量的特征，使用jamovi 2.3.17软件（2022年9月发布，jamovi项目，从https://www.jamovi.org获取）对数据进行统计分析。
研究结果显示，89%的患者为女性，78.7%的患者年龄在55岁以下，年龄范围为14至85岁。已婚状态占我们病例的75.25%。个人癌症史和甲状腺癌家族史分别占0.9%和1.17%。关于组织学特征，主要组织学类型是乳头状甲状腺癌（PTC），占93%。在这1283例病例中，滤泡变异型最为常见（42.89%）。此外，43.80%的肿瘤大小小于2厘米，21.60%的肿瘤有包膜。此外，我们根据美国癌症联合委员会第8版癌症分期系统对数据进行分期，结果显示在诊断时，94.13%的患者处于I期。
本研究概述了摩洛哥DTC的流行病学和组织学特征。研究结果突出了摩洛哥患者临床表现和流行病学特征之间的多样性和差异，有助于更好地理解该疾病并促进适应性管理。
