Fouhi Majdouline El, Benider Abdellatif, Gaëtan Kagambega Zoewendbem Arsène, Mesfioui Abdelhalim
Laboratoire de Génétique-Neuro-Endocrinologie-Biotechnologie, Faculté des Sciences, Université Ibn Tofail, Kénitra, Maroc.
Radiothérapie Oncologique, Centre Mohamed VI pour le Traitement des Cancers, CHU Ibn Rochd, Casablanca, Maroc.
Pan Afr Med J. 2020 Sep 9;37:41. doi: 10.11604/pamj.2020.37.41.21336. eCollection 2020.
The present study aims to determine the various epidemiological characteristics among newly diagnosed patients with breast cancer in Casablanca during 2018. During that period, 668 cases were collected, the average age was 51.6 years, the female was the most represented with 662 cases (99.1%) and men with 6 cases (0.9%), a sex ratio (M/F) of 0.009. The average age of menopause was 49.8 years and the average age of menarche was 13.5 years, 31.7% had a history of cancer (breast 14.1%, stomach and 9% liver 7%). The average diagnosis delay was 10 months, the thyroid disease was the most represented pathology, the left breast was diagnosed in 50.2% and the right breast in 44.7% and 1.3% in the bilateral location. The most common histological type was invasive ductal carcinoma (73.2%). The vascular and lymphatic invasion was observed in 42.2%, axillary nodes were affected in 71.1% of cases. The histological prognosis (SBR) revealed a predominance of grade II in 55.9% of cases. The Luminal B continues to be the most common phenotype (46%) followed by Triple Negative (15.3%) and Luminal A (14.2%) and HER2 (7.4%). The immediate prognosis is a cause for concern because of delayed diagnosis. It seems urgent to develop the health information policy and education.
本研究旨在确定2018年卡萨布兰卡新诊断乳腺癌患者的各种流行病学特征。在此期间，共收集到668例病例，平均年龄为51.6岁，女性占大多数，有662例（99.1%），男性有6例（0.9%），性别比（男/女）为0.009。绝经平均年龄为49.8岁，初潮平均年龄为13.5岁，31.7%有癌症病史（乳腺癌14.1%，胃癌9%，肝癌7%）。平均诊断延迟为10个月，甲状腺疾病是最常见的病理类型，左侧乳腺诊断率为50.2%，右侧乳腺为44.7%，双侧为1.3%。最常见的组织学类型是浸润性导管癌（73.2%）。观察到血管和淋巴管侵犯的占42.2%，71.1%的病例腋窝淋巴结受累。组织学预后（SBR）显示55.9%的病例以II级为主。Luminal B仍然是最常见的表型（46%），其次是三阴性（15.3%）、Luminal A（14.2%）和HER2（7.4%）。由于诊断延迟，近期预后令人担忧。制定健康信息政策和开展健康教育似乎刻不容缓。
