Servicio de Otorrinolaringología, Hospital Universitario La Paz, Madrid, Spain.
Servicio de Otorrinolaringología, Hospital Infanta Leonor, Madrid, Spain.
Acta Otorrinolaringol Esp (Engl Ed). 2024 Mar-Apr;75(2):108-128. doi: 10.1016/j.otoeng.2023.10.005. Epub 2024 Feb 10.
Vestibular schwannoma (VS) is the most common tumour of the cerebellopontine angle. The greater accessibility to radiological tests has increased its diagnosis. Taking into account the characteristics of the tumour, the symptoms and the age of the patient, three therapeutic strategies have been proposed: observation, surgery or radiotherapy. Choosing the most appropriate for each patient is a frequent source of controversy.
This paper includes an exhaustive literature review of issues related to VS that can serve as a clinical guide in the management of patients with these lesions. The presentation has been oriented in the form of questions that the clinician usually asks himself and the answers have been written and/or reviewed by a panel of national and international experts consulted by the Otology Commission of the SEORL-CCC.
A list has been compiled containing the 13 most controversial thematic blocks on the management of VS in the form of 50 questions, and answers to all of them have been sought through a systematic literature review (articles published on PubMed and Cochrane Library between 1992 and 2023 related to each thematic area). Thirty-three experts, led by the Otology Committee of SEORL-CCC, have analyzed and discussed all the answers. In Annex 1, 14 additional questions divided into 4 thematic areas can be found.
This clinical practice guideline on the management of VS offers agreed answers to the most common questions that are asked about this tumour. The absence of sufficient prospective studies means that the levels of evidence on the subject are generally medium or low. This fact increases the interest of this type of clinical practice guidelines prepared by experts.
前庭神经鞘瘤(VS)是桥小脑角最常见的肿瘤。影像学检查的广泛应用提高了其诊断率。鉴于肿瘤的特征、症状和患者的年龄,提出了三种治疗策略:观察、手术或放射治疗。选择最适合每个患者的策略是一个经常引起争议的问题。
本文对与 VS 相关的问题进行了全面的文献回顾,可为这些病变患者的管理提供临床指导。该论文以临床医生通常会提出的问题的形式呈现,并由 SEORL-CCC 的耳科委员会咨询的国家和国际专家小组进行了书面撰写和/或审查。
以 50 个问题的形式编制了一份包含 VS 管理中最具争议的 13 个专题领域的清单,并通过系统的文献回顾(在 1992 年至 2023 年期间在 PubMed 和 Cochrane 图书馆上发表的与每个专题领域相关的文章)寻求了所有问题的答案。由 SEORL-CCC 的耳科委员会领导的 33 名专家对所有答案进行了分析和讨论。在附件 1 中,还可以找到分为 4 个专题领域的另外 14 个问题。
这份关于 VS 管理的临床实践指南提供了对有关这种肿瘤的最常见问题的共识答案。缺乏足够的前瞻性研究意味着该主题的证据水平通常为中等或低等。这一事实增加了由专家编写的这类临床实践指南的兴趣。