Department of Clinical and Experimental Sciences, SSD Endocrinologia, University of Brescia, Azienda Socio-Sanitaria Territoriale (ASST) Spedali Civili di Brescia, Brescia, Italy.
Istituti Clinici Scientifici Maugeri IRCCS, Unit of Internal Medicine and Endocrinology, Laboratory for Endocrine Disruptors, Pavia, Italy.
Aging Male. 2024 Dec;27(1):2310303. doi: 10.1080/13685538.2024.2310303. Epub 2024 Feb 12.
To evaluate the effect of thyroid function on male fertility, focusing on hypo- and hyperthyroidism.
A PubMed/MEDLINE, Web of Science, and Scopus research was performed. Original studies in English published online up to 31 May 2023 were selected and reviewed. The final reference list was defined based on the relevance of each paper to the scope of this review.
The available data in animals (31 studies) and human (26 studies) showed conflicting results. However, thyroid dysfunction altered erection and ejaculation both in animal models than in men.
Both hypothyroidism and hyperthyroidism seem to cause ejaculation and erectile dysfunction. Hence, Guidelines recommend against the systematic screening for thyroid disorders in the men in sub-fertile couples, but only in men with ejaculation and erectile dysfunction and/or altered semen parameters.
评估甲状腺功能对男性生育力的影响，重点关注甲状腺功能减退和甲状腺功能亢进。
对 PubMed/MEDLINE、Web of Science 和 Scopus 进行了研究。选择了截至 2023 年 5 月 31 日在线发表的英语原创研究，并进行了回顾。最终的参考文献列表是根据每篇论文与本综述范围的相关性确定的。
动物（31 项研究）和人类（26 项研究）的现有数据得出了相互矛盾的结果。然而，甲状腺功能障碍改变了动物模型和男性的勃起和射精功能。
甲状腺功能减退和甲状腺功能亢进似乎都会导致射精和勃起功能障碍。因此，指南建议不在生育力低下的夫妇中对男性进行甲状腺疾病的系统筛查，但仅对存在射精和勃起功能障碍和/或精液参数改变的男性进行筛查。
