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冠状动脉微血管功能障碍中的单核苷酸多态性

Single Nucleotide Polymorphisms in Coronary Microvascular Dysfunction.

作者信息

Stein Andrew P, Harder Jonathan, Holmes Henry R, Merz C Noel Bairey, Pepine Carl J, Keeley Ellen C

机构信息

Department of Medicine University of Florida Gainesville FL USA.

Barbra Streisand Women's Heart Center Smidt Heart Institute, Cedars-Sinai Medical Center Los Angeles CA USA.

出版信息

J Am Heart Assoc. 2024 Feb 20;13(4):e032137. doi: 10.1161/JAHA.123.032137. Epub 2024 Feb 13.

DOI:10.1161/JAHA.123.032137
PMID:38348798
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11010085/
Abstract

Coronary microvascular dysfunction is an underdiagnosed pathologic process that is associated with adverse clinical outcomes. There are data to suggest that coronary microvascular dysfunction, in some cases, may be genetically determined. We present an updated review of single nucleotide polymorphisms in coronary microvascular dysfunction.

摘要

冠状动脉微血管功能障碍是一种诊断不足的病理过程，与不良临床结局相关。有数据表明，在某些情况下，冠状动脉微血管功能障碍可能由基因决定。我们对冠状动脉微血管功能障碍中的单核苷酸多态性进行了最新综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e86d/11010085/0bb6fcc8d935/JAH3-13-e032137-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e86d/11010085/0bb6fcc8d935/JAH3-13-e032137-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e86d/11010085/0bb6fcc8d935/JAH3-13-e032137-g001.jpg

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本文引用的文献

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Relationship between inflammatory markers and coronary slow flow in type 2 diabetic patients.2 型糖尿病患者炎症标志物与冠状动脉慢血流的关系。
BMC Cardiovasc Disord. 2023 May 9;23(1):244. doi: 10.1186/s12872-023-03275-y.
2
Coronary Slow Flow Is Not Diagnostic of Microvascular Dysfunction in Patients With Angina and Unobstructed Coronary Arteries.心绞痛且冠状动脉无阻塞患者中，冠状动脉血流缓慢并不提示微血管功能障碍。
J Am Heart Assoc. 2023 Jan 3;12(1):e027664. doi: 10.1161/JAHA.122.027664. Epub 2022 Dec 24.
3
Understanding the pathogenesis of coronary slow flow: Recent advances.
Expanding landscape of coronary microvascular disease in co-morbid conditions: Metabolic disease and beyond.
合并症中心血管疾病的微血管病变：代谢疾病及其他。
J Mol Cell Cardiol. 2024 Jul;192:26-35. doi: 10.1016/j.yjmcc.2024.05.004. Epub 2024 May 10.
理解冠状动脉慢血流的发病机制：最新进展。
Trends Cardiovasc Med. 2024 Apr;34(3):137-144. doi: 10.1016/j.tcm.2022.12.001. Epub 2022 Dec 11.
4
Endothelial nitric oxide synthase Asp298Glu (894G/T) gene polymorphism as a possible risk factor for the coronary slow flow phenomenon among Iranians.内皮型一氧化氮合酶 Asp298Glu（894G/T）基因多态性可能是伊朗人心血管慢流现象的一个危险因素。
BMC Cardiovasc Disord. 2022 Jun 30;22(1):300. doi: 10.1186/s12872-022-02736-0.
5
Prevalence of Coronary Microvascular Disease and Coronary Vasospasm in Patients With Nonobstructive Coronary Artery Disease: Systematic Review and Meta-Analysis.非阻塞性冠状动脉疾病患者中冠状动脉微血管疾病和冠状动脉痉挛的患病率：系统评价和荟萃分析。
J Am Heart Assoc. 2022 Apr 5;11(7):e023207. doi: 10.1161/JAHA.121.023207. Epub 2022 Mar 18.
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An Evaluation of the Role of Oxidative Stress in Non-Obstructive Coronary Artery Disease.氧化应激在非阻塞性冠状动脉疾病中的作用评估
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Myocardial infarction with non-obstructive coronary artery disease.非阻塞性冠状动脉疾病性心肌梗死。
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Cardiac myosin contraction and mechanotransduction in health and disease.心脏肌球蛋白收缩和机械转导在健康和疾病中的作用。
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