Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
EuroIntervention. 2021 Dec 3;17(11):e875-e887. doi: 10.4244/EIJ-D-21-00426.
As a result of the increased use of coronary angiography in acute myocardial infarction in the last two decades, myocardial infarction with non-obstructive coronary arteries (MINOCA) has received growing attention in everyday clinical practice. At the same time, research interest in MINOCA has increased significantly. MINOCA is a heterogeneous disease entity seen in 5-10% of all patients with myocardial infarction, especially in women. Clinically, MINOCA may be difficult to distinguish from other non-ischaemic conditions that can cause similar symptoms and myocardial injury. There is still some confusion around the diagnosis, investigation and management of patients with MINOCA. The present review summarises the current knowledge of MINOCA regarding epidemiology, pathophysiology, investigation, and treatment, with a special focus on imaging modalities. In addition, remaining important knowledge gaps are highlighted.
由于在过去二十年中冠状动脉造影术在急性心肌梗死中的应用增加，非阻塞性冠状动脉心肌梗死（MINOCA）在日常临床实践中受到越来越多的关注。与此同时，MINOCA 的研究兴趣显著增加。MINOCA 是一种异质性疾病实体，见于所有心肌梗死患者的 5-10%，尤其是女性。临床上，MINOCA 可能难以与其他可引起类似症状和心肌损伤的非缺血性疾病区分。MINOCA 患者的诊断、检查和治疗仍存在一些混淆。本综述总结了 MINOCA 在流行病学、病理生理学、检查和治疗方面的最新知识，特别关注影像学方法。此外，还强调了仍然存在的重要知识空白。
