Department of General Surgery and Transplantation, Pomeranian Medical University in Szczecin, Poland.
Klinik fur Innere Medizin. Gastroenterologie, Nephrologie, Haematologie und Onkologie. Asklepios Klinikum Uckermark, Schwedt, Germany.
Pol Przegl Chir. 2023 Oct 12;96(0):84-87. doi: 10.5604/01.3001.0053.9252.
<b><br>Introduction:</b> The results of some studies show that predictors of less favourable outcomes of surgery for carpal tunnel syndrome might include the presence of comorbidities, such as diabetes and thyroid gland diseases. The role of these factors has not been clearly determined, but in most trials the patients burdened with comorbidities conducive to CTS are excluded from the analysis.</br> <b><br>Aim:</b> The aim of this study was to investigate the effect of concomitant diseases on the clinical profile and outcomes of surgery for carpal tunnel syndrome.</br> <b><br>Material and methods:</b> The study group consisted of 1117 patients - 909 women (81%) and 208 men (19%) - at a mean age of 63 years. A total of 972 patients (87%) declared having at least one comorbidity, whereas 145 patients (13%) declared no comorbidities. The measurements were performed preoperatively and at 6 months postoperatively; they included pain intensity, total grip and key-pinch strength, digital sensibility and hand function with Levine's questionnaire.</br> <b><br>Results:</b> At baseline, the patients with comorbidities had significantly worse digital sensiblility, weaker total grip strength and greater functional impairment of the hand, but only grip strength reached the minimal important difference (3.5 kg). Carpal tunnel release resulted in significant improvement in the tested variables for all patients, although the outcomes at 6 months were less favourable for those with comorbidities with regard to digital sensiblility, total grip and pinch strength and function of the hand. All these differences were statistically significant, but only grip strength reached the minimal important difference (2.9 kg).</br> <b><br>Conclusion:</b> The results of this study show that comorbidities in patients suffering from CTS had a statistically and clinically significant negative effect only on the total grip strength pre- and postoperatively, and no significant effect on the outcome of surgery, which was satisfactory in all patients.</br>.
<b><br>引言：</b>一些研究结果表明，腕管综合征手术预后不良的预测因素可能包括合并症的存在，如糖尿病和甲状腺疾病。这些因素的作用尚未明确确定，但在大多数试验中，患有有利于 CTS 的合并症的患者被排除在分析之外。</br> <b><br>目的：</b>本研究旨在探讨并存疾病对腕管综合征手术临床特征和结果的影响。</br> <b><br>材料与方法：</b>研究组包括 1117 名患者-909 名女性（81%）和 208 名男性（19%）-平均年龄 63 岁。共有 972 名患者（87%）报告至少有一种合并症，而 145 名患者（13%）报告没有合并症。测量在术前和术后 6 个月进行；它们包括疼痛强度、总握力和关键捏力、数字感觉和 Levine 问卷的手部功能。</br> <b><br>结果：</b>基线时，合并症患者的数字感觉明显较差，总握力较弱，手部功能障碍较大，但只有握力达到了最小重要差异（3.5 公斤）。腕管松解术使所有患者的测试变量均显著改善，尽管合并症患者的数字感觉、总握力和捏力以及手部功能在 6 个月时的结果较差。所有这些差异均具有统计学意义，但只有握力达到了最小重要差异（2.9 公斤）。</br> <b><br>结论：</b>本研究结果表明，患有 CTS 的患者的合并症仅对术前和术后的总握力有统计学和临床意义的负面影响，对手术结果没有显著影响，所有患者的手术结果均令人满意。</br>。
