Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Department of Emergency@Trauma Center, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Ann Surg Oncol. 2024 May;31(5):3212-3221. doi: 10.1245/s10434-024-14909-6. Epub 2024 Feb 13.
Traditionally, surgical treatment is recommended for right-sided colonic cancer obstruction (RCCO); however, the literature comparing surgical or non-surgical procedures is lacking.
Patients included in this study were divided into two groups: one group received elective surgery after self-expanding metal stent (SEMS) placement, i.e., the bridge to surgery (BTS) group, and one group received emergency surgery (ES).
Thirty-five patients were included in the BTS group and 60 patients underwent ES. The technical and clinical success rates for SEMS placement were 100% and 88.6%, respectively, while the short-term complication rates were 51.4% and 33.3% for the BTS and ES groups, respectively (p = 0.082). Overall, 2.9% and 3.3% of postoperative deaths occurred in the BTS and ES groups (p = 1.000). The 1-year overall survival (OS) rates were 91.4% and 88.3% (p = 0.840), 3-year OS rates were 85.7% and 81.7% (p = 0.860), and 5-year OS rates were 82.9% and 76.7% (p = 0.620) in the BTS and ES groups, respectively. No tumor recurrence was found in the BTS group but seven recurrences were found in the ES group (11.7%) [p = 0.091]. Laparoscopic surgery was chosen by 42.9% of patients in the BTS group and 26.7% of patients in the ES group (p = 0.104); however, the length of hospital stay (p = 0.001) was longer in the BTS group.
In the two groups, no differences were found in terms of postoperative complications and mortality as well as OS. The BTS group preferred to perform laparoscopic surgery and the technical success rate of stenting was high, therefore SEMS for RCCO was considered safe and feasible.
传统上,建议对右侧结肠癌梗阻(RCCO)进行手术治疗;然而,缺乏比较手术和非手术治疗方法的文献。
本研究将患者分为两组:一组在自膨式金属支架(SEMS)放置后接受择期手术,即桥接手术(BTS)组,另一组接受急诊手术(ES)。
BTS 组纳入 35 例患者,ES 组纳入 60 例患者。SEMS 放置的技术和临床成功率分别为 100%和 88.6%,而 BTS 和 ES 组的短期并发症发生率分别为 51.4%和 33.3%(p=0.082)。总体而言,BTS 和 ES 组的术后死亡率分别为 2.9%和 3.3%(p=1.000)。BTS 和 ES 组的 1 年总生存率(OS)分别为 91.4%和 88.3%(p=0.840),3 年 OS 率分别为 85.7%和 81.7%(p=0.860),5 年 OS 率分别为 82.9%和 76.7%(p=0.620)。BTS 组未发现肿瘤复发,但 ES 组发现 7 例复发(11.7%)[p=0.091]。BTS 组中 42.9%的患者选择腹腔镜手术,而 ES 组中 26.7%的患者选择腹腔镜手术(p=0.104);然而,BTS 组的住院时间更长(p=0.001)。
两组患者术后并发症和死亡率以及 OS 无差异。BTS 组更倾向于进行腹腔镜手术,支架置入的技术成功率较高,因此 SEMS 治疗 RCCO 是安全可行的。