Gibson J M
Blood Cells. 1985;11(2):301-7, 309-10.
The use of preserved blood for quality control is well established. The treatment of such materials to extend their life can impart a property to those materials such that external contaminants to diluents used for subsequent analysis may not be detected by these materials and give a false sense of security in a quality control program. The effect of the contaminant on fresh cells is more of a problem. Most contaminants affect cell volume, particularly the red cells which have been studied in-depth. White cell differential screening by size analysis is similarly affected. The recognition of the different properties of fresh and preserved blood helps explain results.
使用保存血液进行质量控制已得到充分确立。对这类材料进行处理以延长其使用寿命,可能会赋予这些材料一种特性,使得用于后续分析的稀释剂中的外部污染物可能无法被这些材料检测到,从而在质量控制程序中给人一种虚假的安全感。污染物对新鲜细胞的影响更是一个问题。大多数污染物会影响细胞体积,尤其是已经深入研究过的红细胞。通过大小分析进行白细胞分类筛查也会受到类似影响。认识到新鲜血液和保存血液的不同特性有助于解释检测结果。