Department of Cardiology and Electrotherapy, Medical University of Gdańsk, Smoluchowskiego 17 Street, 80-214 Gdańsk, Poland.
Division of Biostatistics and Neural Networks, Medical University of Gdańsk, Dębinki 1 Street, 80-211 Gdansk, Poland.
J Interv Cardiol. 2024 Feb 5;2024:5524668. doi: 10.1155/2024/5524668. eCollection 2024.
Ventricular electrical storm (VES) is characterized by the occurrence of multiple episodes of sustained ventricular arrhythmias (VA) over a short period of time. Radiofrequency ablation (RFA) has been reported as an effective treatment in patients with ventricular tachycardia (VT).
The aim of the present study was to indicate the short-term and long-term predictors of recurrent VA after RFA was performed due to VES.
A retrospective, single-centre study included patients, who had undergone RFA due to VT between 2012 and 2021. In terms of the short-term (at the end of RFA) effectiveness of RFA, the following scenarios were distinguished: complete success: inability to induce any VT; partial success: absence of clinical VT; failure: inducible clinical VT. In terms of the long-term (12 months) effectiveness of RFA, the following scenarios were distinguished: effective ablation: no recurrence of any VT; partially successful ablation: VT recurrence; ineffective ablation: VES recurrence.
The study included 62 patients. Complete short-term RFA success was obtained in 77.4% of patients. The estimated cumulative VT-free survival and VES-free survival were, respectively, 28% and 33% at the 12-month follow-up. Ischemic cardiomyopathy and complete short-term RFA success were predictors of long-term RFA efficacy. Neutrophil to lymphocyte ratio (NLR) and GFR <60 mL/min/1.73 m were associated with VES recurrence. NLR ≥2.95 predicted VT and/or VES recurrence with a sensitivity of 66.7% and specificity of 72.2%.
Ischemic cardiomyopathy and short-term complete success of RFA were predictors of no VES recurrence during the 12-month follow-up, while NLR and GFR <60 ml/min/1.73 m were associated with VES relapse.
室性电风暴（VES）的特征是在短时间内发生多次持续性室性心律失常（VA）。射频消融（RFA）已被报道为治疗室性心动过速（VT）的有效方法。
本研究旨在指出由于 VES 而行 RFA 后复发性 VA 的短期和长期预测因素。
一项回顾性、单中心研究纳入了 2012 年至 2021 年期间因 VT 而行 RFA 的患者。根据 RFA 的短期（RFA 结束时）效果，区分了以下情况：完全成功：无法诱导任何 VT；部分成功：无临床 VT；失败：可诱导临床 VT。根据 RFA 的长期（12 个月）效果，区分了以下情况：有效消融：无任何 VT 复发；部分成功消融：VT 复发；无效消融：VES 复发。
该研究纳入了 62 例患者。77.4%的患者获得了完全的短期 RFA 成功。在 12 个月的随访中，估计无 VT 生存和无 VES 生存的累积率分别为 28%和 33%。缺血性心肌病和完全的短期 RFA 成功是长期 RFA 疗效的预测因素。中性粒细胞与淋巴细胞比值（NLR）和 GFR<60ml/min/1.73m 与 VES 复发相关。NLR≥2.95 预测 VT 和/或 VES 复发的灵敏度为 66.7%，特异性为 72.2%。
缺血性心肌病和 RFA 的短期完全成功是 12 个月随访期间无 VES 复发的预测因素，而 NLR 和 GFR<60ml/min/1.73m 与 VES 复发相关。
