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三种沸石咪唑酯骨架及其衍生的氧化锌纳米颗粒的抗菌活性。

The antibacterial activity of three zeolitic-imidazolate frameworks and zinc oxide nanoparticles derived from them.

作者信息

Khattami Kermanshahi Pouya, Akhbari Kamran

机构信息

School of Chemistry, College of Science, University of Tehran P.O. Box 14155-6455 Tehran Iran

出版信息

RSC Adv. 2024 Feb 13;14(8):5601-5608. doi: 10.1039/d4ra00447g. eCollection 2024 Feb 7.

DOI:10.1039/d4ra00447g
PMID:38352679
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10862664/
Abstract

Zinc has been widely studied for its antibacterial properties due to its low toxicity, availability, and low cost. This research focused on analysing the antibacterial effects of three types of MOFs (metal-organic frameworks) with zinc as the central metal: ZIF-4, ZIF-7, and ZIF-8. The study found that ZIF-8 had the strongest antibacterial effect, while ZIF-7 had the weakest among them. These findings were consistent with the results of the ICP (inductively coupled plasma) analysis, which measured the amount of zinc released. Additionally, the antibacterial effect of ZIF-8 was found to be higher than that of zinc oxide species obtained from calcination of the compounds. Among the zinc oxide samples, ZnO nanoparticles which derived from ZIF-4 showed the highest antibacterial activity.

摘要

由于锌的低毒性、易获取性和低成本，其抗菌性能已得到广泛研究。本研究聚焦于分析三种以锌为中心金属的金属有机框架（MOF）：ZIF-4、ZIF-7和ZIF-8的抗菌效果。研究发现，ZIF-8的抗菌效果最强，而ZIF-7的抗菌效果最弱。这些发现与电感耦合等离子体（ICP）分析结果一致，该分析测量了锌的释放量。此外，发现ZIF-8的抗菌效果高于通过化合物煅烧获得的氧化锌类物质。在氧化锌样品中，源自ZIF-4的ZnO纳米颗粒表现出最高的抗菌活性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f85c/10862664/5aa82903df51/d4ra00447g-f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f85c/10862664/72919005b052/d4ra00447g-f1.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f85c/10862664/498ada5afa42/d4ra00447g-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f85c/10862664/594d5fcd7abe/d4ra00447g-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f85c/10862664/526658268f86/d4ra00447g-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f85c/10862664/5aa82903df51/d4ra00447g-f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f85c/10862664/72919005b052/d4ra00447g-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f85c/10862664/45178ee75f9b/d4ra00447g-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f85c/10862664/498ada5afa42/d4ra00447g-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f85c/10862664/594d5fcd7abe/d4ra00447g-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f85c/10862664/526658268f86/d4ra00447g-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f85c/10862664/5aa82903df51/d4ra00447g-f6.jpg

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