Department of Dermatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Department of Health Sciences, Community and Occupational Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Contact Dermatitis. 2024 Apr;90(4):372-377. doi: 10.1111/cod.14510. Epub 2024 Feb 14.
To date, hand eczema (HE)-related presenteeism has never been assessed within the general population, and general population-based studies on HE-related sickness absence are limited.
To assess the prevalence of HE-related presenteeism and sickness absence, and factors associated with HE-related presenteeism, within the Dutch general population.
Within the Lifelines Cohort Study, participants with HE in the last year (aged 18-65 in 2020), were identified by a questionnaire including questions regarding HE-related presenteeism and sickness absence. Socio-demographic factors were collected from 2006 to 2020.
Out of the 3.703 included participants with HE, 2.7% (n = 100) reported HE-related presenteeism, with 19.8% (n = 57) among those with severe-to-very-severe HE. HE-related sickness absence was reported by 0.5% (n = 20) and 5.9% (n = 17), respectively. Logistic regression analyses, adjusted for age and sex, showed negative associations between HE-related presenteeism and higher educational attainment, higher income (>€2500) and higher occupational skill level, and positive associations for high-risk occupations, chronic HE, moderate and severe-to-very-severe HE (compared to almost clear), atopic dermatitis and occupational wet exposure.
A high prevalence of HE-related presenteeism was found among participants with severe-to-very-severe HE. Future studies should focus on longitudinal associations with the clinical course of HE, as HE-related presenteeism might aggravate symptoms of HE.
迄今为止，手部湿疹（HE）相关的出勤主义在普通人群中从未被评估过，而基于普通人群的 HE 相关缺勤研究也很有限。
评估荷兰普通人群中 HE 相关出勤主义和缺勤的患病率，以及与 HE 相关出勤主义相关的因素。
在 Lifelines 队列研究中，通过包括有关 HE 相关出勤主义和缺勤问题的问卷，确定了过去一年中患有 HE（2020 年年龄在 18-65 岁之间）的参与者。社会人口统计学因素从 2006 年至 2020 年收集。
在 3703 名纳入的 HE 参与者中，2.7%（n=100）报告存在 HE 相关出勤主义，其中严重至非常严重 HE 者占 19.8%（n=57）。分别有 0.5%（n=20）和 5.9%（n=17）报告存在 HE 相关缺勤。经年龄和性别调整的逻辑回归分析显示，HE 相关出勤主义与较高的教育程度、较高的收入（>€2500）和较高的职业技能水平呈负相关，而与高风险职业、慢性 HE、中重度至非常严重 HE（与几乎清晰相比）、特应性皮炎和职业湿暴露呈正相关。
在患有严重至非常严重 HE 的参与者中，发现了很高的 HE 相关出勤主义患病率。未来的研究应重点关注与 HE 临床病程的纵向关联，因为 HE 相关出勤主义可能会加重 HE 的症状。
