University of Groningen, University Medical Center Groningen, Department of Dermatology, The Netherlands.
J Dtsch Dermatol Ges. 2019 Feb;17(2):158-166. doi: 10.1111/ddg.13754.
Studies of beekeepers have mostly focused on contact allergy to propolis. The overall prevalence of hand eczema (HE) in beekeepers has not been studied. Our objectives were to gain insight into the prevalence of HE in the Dutch beekeeper population; to define the impact of beekeeping activities on HE and vice versa; and to determine associated factors.
We used a cross-sectional online survey. Dutch beekeepers answered questions on beekeeping activities, the prevalence and characteristics of HE, including severity, and the impact of the disease on beekeeping.
We analyzed 833 surveys (12 % of Dutch beekeepers). The one-year prevalence of HE was 13.2 %, and the lifetime prevalence was 20.5 %. In 28 patch-tested beekeepers with hand eczema, eight (28.6 %) were allergic to propolis. Atopic dermatitis was the only variable associated with HE: the odds ratio was 4.53 (95 % confidence interval 2.78-7.38). One in three beekeepers reported that HE was caused or worsened by beekeeping, although only 3.8 % reported working less at beekeeping because of HE, and the impact of HE on beekeeping activities (as perceived by beekeepers) is low.
In this sample of Dutch beekeepers, hand eczema was more prevalent than in the general population, but seems to have had little impact on the beekeeping activities of the majority of beekeepers.
有关养蜂人的研究大多集中于对蜂胶的接触过敏。养蜂人手部湿疹（HE）的总体患病率尚未得到研究。我们的目的是深入了解荷兰养蜂人群体中 HE 的患病率；定义养蜂活动对 HE 的影响及其反之亦然；并确定相关因素。
我们使用了横断面在线调查。荷兰养蜂人回答了有关养蜂活动、HE 的患病率和特征（包括严重程度）以及疾病对养蜂的影响的问题。
我们分析了 833 份调查（占荷兰养蜂人的 12%）。HE 的一年患病率为 13.2%，终身患病率为 20.5%。在 28 名患有手部湿疹的斑贴试验养蜂人中，有 8 名（28.6%）对蜂胶过敏。特应性皮炎是唯一与 HE 相关的变量：比值比为 4.53（95%置信区间 2.78-7.38）。三分之一的养蜂人报告说 HE 是由养蜂引起或加重的，尽管只有 3.8%的养蜂人因为 HE 而减少了养蜂工作，并且 HE 对养蜂活动的影响（养蜂人认为）很低。
在荷兰养蜂人样本中，手部湿疹的患病率高于一般人群，但似乎对大多数养蜂人的养蜂活动影响不大。
