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肥胖和体重指数:骨关节炎研究中的过去和未来考虑因素。

Obesity and body mass index: Past and future considerations in osteoarthritis research.

机构信息

Department of Agricultural, Food, and Nutritional Science, University of Alberta, Edmonton, AB, Canada.

Department of Medicine, University of Toronto, Toronto, ON, Canada.

出版信息

Osteoarthritis Cartilage. 2024 Apr;32(4):452-459. doi: 10.1016/j.joca.2024.02.003. Epub 2024 Feb 12.

Abstract

Obesity is an important topic for the osteoarthritis (OA) scientific community. However, the predominant use of body mass index (BMI) to define obesity in OA research is associated with uncertainties and limitations. These include an inability to discern fat and muscle mass, account for sex-differences in fat distribution, or identify adiposity-related health impairments. A focus on BMI in OA research may influence weight bias in clinical practice and impact disparities in access to effective OA treatments. To ensure that our understanding and approaches to improve health outcomes for individuals with or at risk for OA continues to advance in the next decade, future research will need to consider alternative measures beyond BMI for obesity identification and align with evolving obesity science. OA researchers must be aware of issues associated with weight stigma and work to minimize negative generalizations based on BMI.

摘要

肥胖是骨关节炎(OA)科学界的一个重要课题。然而,在 OA 研究中,主要使用体重指数(BMI)来定义肥胖,这与不确定性和局限性有关。这些问题包括无法区分脂肪和肌肉质量、无法解释男女之间脂肪分布的差异,或者无法确定与肥胖相关的健康损害。在 OA 研究中关注 BMI,可能会影响临床实践中的体重偏见,并影响获得有效 OA 治疗的机会的差异。为了确保我们在下一个十年内继续深入了解和寻求改善 OA 患者或有患病风险的个体的健康结果的方法,未来的研究需要考虑 BMI 以外的替代方法来识别肥胖,并与不断发展的肥胖科学保持一致。OA 研究人员必须意识到与体重歧视相关的问题,并努力减少基于 BMI 的负面概括。

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