Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA
Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Reg Anesth Pain Med. 2024 Sep 2;49(9):688-691. doi: 10.1136/rapm-2023-105235.
Over time, the focus of evidence-based acute pain medicine has shifted, from a focus on drugs and interventions (characterized by numbers needed to treat), to an appreciation of procedure-specific factors (characterized by guidelines and meta-analyses), and now anesthesiologists face the challenge to integrate our current approach with the concept of precision medicine. Psychometric and biopsychosocial markers can potentially guide clinicians on who may need more aggressive perioperative pain management, or who would respond particularly well to a given analgesic intervention. The challenge will be to identify an easily assessable set of parameters that will guide perioperative physicians in tailoring the analgesic strategy to procedure and patient.
随着时间的推移，循证急性疼痛医学的重点已经转移，从关注药物和干预措施（以需要治疗的人数为特征），到认识到特定程序的因素（以指南和荟萃分析为特征），现在麻醉师面临着将我们目前的方法与精准医学概念相结合的挑战。心理计量和生物心理社会标志物有可能指导临床医生确定哪些患者可能需要更积极的围手术期疼痛管理，或者哪些患者对特定的镇痛干预措施反应特别好。挑战将是确定一组易于评估的参数，这些参数将指导围手术期医生根据手术和患者来定制镇痛策略。
