Alqaraishi Ali, Tawhari Mohammed, Alyahya Nawaf M, Alotaibi Alanoud, Ghoulah Alanoud, Aledrees Abdulrahman, Alabdulsalam Abdulrahman
Internal Medicine, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Research Center, King Abdullah International Medical Research Centre, Riyadh, SAU.
Nephrology, King Abdulaziz Medical City, Riyadh, SAU.
Cureus. 2024 Jan 15;16(1):e52304. doi: 10.7759/cureus.52304. eCollection 2024 Jan.
Acute tubular necrosis (ATN) is a serious medical condition characterized by the rapid destruction of renal tubular epithelial cells, resulting in acute kidney injury, given its multifactorial etiologies, which can include nephrotoxic agents, ischemic insults, hypovolemia, and sepsis. We report the case of a young male patient who presented with recurrent worsening kidney function with bland sediment that was confirmed with multiple kidney biopsies as recurrent attacks of ATN of unclear etiology, which did not respond to supportive measures but did respond to steroids.
急性肾小管坏死(ATN)是一种严重的医学病症,其特征是肾小管上皮细胞迅速破坏,导致急性肾损伤。鉴于其多因素病因,包括肾毒性药物、缺血性损伤、血容量不足和败血症等。我们报告了一例年轻男性患者的病例,该患者反复出现肾功能恶化,尿沉渣正常,经多次肾活检证实为病因不明的复发性ATN发作,对支持性措施无反应,但对类固醇有反应。