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[大肠杆菌uvrA crp菌株对紫外线的敏感性增强]

[Enhanced UV sensitivity of Escherichia coli strain uvrA crp].

作者信息

Skavronskaia A G, Aleshkin G I

出版信息

Genetika. 1979;15(8):1522-4.

PMID:383571
Abstract

UV-sensitivity and UV-induced mutability to tryptophan independence has been studied in isogenic crp, cya, crp+, uvrA crp and uvrA crp+ strains of Escherichia coli. crp and cya strains are found to have the same UV-sensitivity as an isogenic wild type strain. UV-sensitivity of uvrA crp strain seems to be one-two orders increased as compared with the sensitivity exhibited by the uvrA - crp+ strain. The yield of UV-induced revertants is slightly higher in crp, cya and uvrA crp strains than in the wild type cells. The existence of cap-dependent inducible error-free repair pathway is supposed due to the data obtained.

摘要

已在大肠杆菌的同基因crp、cya、crp⁺、uvrA crp和uvrA crp⁺菌株中研究了紫外线敏感性以及紫外线诱导的对色氨酸非依赖性的可突变性。发现crp和cya菌株具有与同基因野生型菌株相同的紫外线敏感性。与uvrA - crp⁺菌株相比,uvrA crp菌株的紫外线敏感性似乎增加了一到两个数量级。crp、cya和uvrA crp菌株中紫外线诱导的回复突变体产量略高于野生型细胞。根据所获得的数据推测存在依赖于CAP的可诱导无差错修复途径。

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