Cakmak Mehmet Erdem
Department of Allergy and Clinical Immunology, Basaksehir Cam and Sakura City Hospital, Istanbul, Turkiye.
North Clin Istanb. 2024 Jan 24;11(1):88-90. doi: 10.14744/nci.2022.45656. eCollection 2024.
Fabry disease is a rare genetic disease caused by a deficiency of α-galactosidase A gene (α-Gal A). Two intravenous enzymes administered every two weeks, agalsidase alfa and beta can slow disease progression and increase survival if administered early, before organ damage occurs. In this case report, we present a patient with a history of anaphylaxis to agalsidase beta who was successfully treated with agalsidase alfa.
法布里病是一种由α-半乳糖苷酶A基因(α-Gal A)缺乏引起的罕见遗传病。每两周静脉注射一次的两种酶,阿加糖酶α和β,如果在器官损伤发生之前尽早给药,可以减缓疾病进展并提高生存率。在本病例报告中,我们介绍了一名对阿加糖酶β有过敏反应病史的患者,该患者成功接受了阿加糖酶α治疗。