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BMC Musculoskelet Disord. 2023 Jun 23;24(1):514. doi: 10.1186/s12891-023-06527-2.
2
Multidisciplinary Treatment of Fracture-Related Infection Has a Positive Impact on Clinical Outcome-A Retrospective Case Control Study at a Tertiary Referral Center.骨折相关感染的多学科治疗对临床结果有积极影响——一项在三级转诊中心进行的回顾性病例对照研究
Antibiotics (Basel). 2023 Jan 21;12(2):230. doi: 10.3390/antibiotics12020230.
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EFORT Open Rev. 2023 Feb 21;8(2):90-99. doi: 10.1530/EOR-22-0076.
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Evidence for Local Antibiotics in the Prevention of Infection in Orthopaedic Trauma.局部使用抗生素预防骨科创伤感染的证据
J Clin Med. 2022 Dec 16;11(24):7461. doi: 10.3390/jcm11247461.
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Comparison of the clinical outcomes between vascularized bone graft and the Masquelet technique for the reconstruction of Gustilo type III open tibial fractures.血管化骨移植与 Masquelet 技术治疗 Gustilo Ⅲ型开放性胫骨骨折的临床疗效比较。
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Epidemiology of Open Tibia fractures presenting to a tertiary referral centre in Southern Malawi: a retrospective study.马拉维南部一家三级转诊中心收治的开放性胫骨骨折的流行病学：一项回顾性研究。
Malawi Med J. 2022 Jun;34(2):118-122. doi: 10.4314/mmj.v34i2.7.
7
What Factors Affect Outcome in the Treatment of Fracture-Related Infection?哪些因素会影响骨折相关感染的治疗结果？
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开放性胫骨骨折中的骨折相关感染

Fracture related infection in open tibial fractures.

作者信息

Craxford Simon, Vris Alexandros, Ahluwalia Raju, Saini Aaron, Harrison William D, Graham Simon, Sharma Hemant

机构信息

Limb Reconstruction Fellow, Royal London Hospital, UK.

Royal London Hospital, UK.

出版信息

J Orthop. 2024 Jan 30;51:98-102. doi: 10.1016/j.jor.2024.01.010. eCollection 2024 May.

DOI:10.1016/j.jor.2024.01.010
PMID:38357441
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10862397/
Abstract

Open tibia fractures frequently occur following high-energy trauma. Contamination of the fracture site combined with limited soft tissue coverage and blood supply means that these open fractures are associated with a high rate of complications, including fracture related infection (FRI). FRI is associated with lowered patient outcomes and requires early recognition and appropriate surgical and medical management. The current evidence on FRI after open tibial fractures largely is limited to case series, small retrospective cohort studies and expert opinion. Recent expert consensus has produced guidelines with the aim of standardising care for these patients. This review summarises the current management strategies employed in treating FRI following open tibial fractures and where possible the evidence behind them.

摘要

开放性胫骨骨折常发生于高能量创伤后。骨折部位的污染，加上软组织覆盖和血供有限，意味着这些开放性骨折会引发高并发症发生率，包括骨折相关感染（FRI）。FRI与患者预后降低相关，需要早期识别并进行适当的手术和药物治疗。目前关于开放性胫骨骨折后FRI的证据在很大程度上仅限于病例系列、小型回顾性队列研究和专家意见。最近的专家共识制定了指南，旨在规范对这些患者的治疗。本综述总结了目前治疗开放性胫骨骨折后FRI所采用的管理策略以及尽可能的相关证据。