Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust and University of Bristol, Bristol, UK.
Bone Joint J. 2022 Jun;104-B(6):736-746. doi: 10.1302/0301-620X.104B6.BJJ-2021-1097.R2.
This study estimated trends in incidence of open fractures and the adherence to clinical standards for open fracture care in England.
Longitudinal data collected by the Trauma Audit and Research Network were used to identify 38,347 patients with open fractures, and a subgroup of 12,170 with severe open fractures of the tibia, between 2008 and 2019 in England. Incidence rates per 100,000 person-years and 95% confidence intervals were calculated. Clinical care was compared with the British Orthopaedic Association Standards for Trauma and National Major Trauma Centre audit standards.
In total, 60% of all open fractures occurred in males; the median age was 48 years (interquartile range (IQR) 29 to 68). Between 2012 and 2019, the overall incidence in England was 6.94 per 100,000 person-years. In males, the highest incidence observed was in those aged 20 to 29 years (11.50 per 100,000 person-years); in females, incidence increased with age, peaking at 32.11/100,000 person-years at 90 years of age and over. Among those with severe open fractures of the tibia, there was a bimodal distribution in males, peaking at 20 to 29 years (3.71/100,000 person-years) and greater than 90 years of age (2.84/100,000 person-years) respectively; among females, incidence increased with age to a peak of 9.91/100,000 person years at 90 years of age and over. There has been variable improvement with time in the clinical care standards for patients with severe open fractures of the tibia. The median time to debridement was 13.0 hours (IQR 6.4 to 20.9); almost two-thirds of patients underwent definitive soft-tissue coverage within 72 hours from 2016 to 2019.
This is the first time the incidence of all open fractures has been studied using data from a national audit in England. While most open fractures occurred in young males, the incidence increased with age in females to a much greater level than observed in older males. The degree of missing data in the national audit is startling, and limits the certainty of inferences drawn concerning open fracture care. Cite this article: 2022;104-B(6):736-746.
本研究旨在评估英格兰开放性骨折发病率的变化趋势和开放性骨折治疗临床标准的遵循情况。
利用创伤审核和研究网络收集的纵向数据,鉴定了 2008 年至 2019 年期间英格兰 38347 例开放性骨折患者和 12170 例严重胫骨开放性骨折患者。计算了每 10 万人年的发病率和 95%置信区间。将临床护理与英国矫形协会创伤标准和国家主要创伤中心审核标准进行比较。
总共,60%的开放性骨折发生在男性;中位年龄为 48 岁(四分位距 29 至 68)。2012 年至 2019 年,英格兰的总体发病率为每 10 万人年 6.94 例。在男性中,观察到的最高发病率发生在 20 至 29 岁人群(每 10 万人年 11.50 例);在女性中,发病率随年龄增长而增加,在 90 岁及以上人群中达到每 10 万人年 32.11 例的峰值。在严重胫骨开放性骨折患者中,男性呈双峰分布,分别在 20 至 29 岁(每 10 万人年 3.71 例)和 90 岁以上(每 10 万人年 2.84 例)达到峰值;在女性中,发病率随年龄增长而增加,在 90 岁及以上人群中达到每 10 万人年 9.91 例的峰值。随着时间的推移,胫骨严重开放性骨折患者的临床护理标准有所改善。清创的中位时间为 13.0 小时(四分位距 6.4 至 20.9);几乎三分之二的患者在 2016 年至 2019 年期间,在受伤后 72 小时内接受了确定性软组织覆盖。
这是首次使用英格兰国家审核数据研究所有开放性骨折的发病率。虽然大多数开放性骨折发生在年轻男性中,但女性的发病率随年龄增长而增加,达到比老年男性更高的水平。国家审核中缺失数据的程度令人震惊,限制了对开放性骨折治疗的推断的确定性。 引用本文:2022;104-B(6):736-746。