Faculty of Dentistry, Periodontology Department, Nigde Omer Halisdemir University, Niğde, Turkey.
Department of Biostatistics and Medical Informatics, Mersin University, Mersin, Turkey.
Aust Dent J. 2024 Sep;69(3):175-181. doi: 10.1111/adj.13011. Epub 2024 Feb 15.
The aim of the study was to compare serum ferritin and iron levels and periodontal status in pre- and post-menopausal female patients.
A total of 108 systemically healthy patients were included in the study, 63 patients in the pre-menopause group and 45 patients in the post-menopause group. The periodontal diagnosis was made according to the new periodontal disease classification of the American Academy of Periodontology and the European Federation of Periodontology Serum Iron (μg/dL) and Serum Ferritin (ng/mL) values were analysed in patients divided into groups according to menopausal status and periodontal status.
The mean ferritin in pre-menopausal women (34.96 ± 27.87 ng/mL) was lower than the mean ferritin in post-menopausal women (64.24 ± 36.05 ng/mL), and this difference was found to be statistically significant (P<0.001). There was no statistically significant difference between the averages of iron and ferritin according to periodontal diagnosis in pre-menopausal women (P = 0.200 and P = 0.858). A statistically significant difference was found between serum ferritin averages according to periodontal diagnosis in post-menopausal women (P < 0.001). Serum ferritin at % Interdental bone loss = 0 in Post-M was 33.93 ± 8.65 ng/mL; 47.51 ± 16.17 ng/mL in Stage 1 periodontitis; 72.66 ± 18.12 ng/mL in Stage 2 periodontitis; It was found to be 87.4 ± 47.1 ng/mL in Stage 3-4 periodontitis.
Serum ferritin values might vary depending on the presence or severity of periodontitis in post-menopausal women.
本研究旨在比较绝经前后女性患者的血清铁蛋白和铁水平及牙周状况。
本研究共纳入 108 例系统性健康患者,其中 63 例为绝经前患者,45 例为绝经后患者。牙周病诊断依据美国牙周病学会和欧洲牙周病学会新的牙周病分类,根据绝经状态和牙周状况将患者分为不同组,分析血清铁(μg/dL)和血清铁蛋白(ng/mL)值。
绝经前女性的平均铁蛋白(34.96±27.87ng/mL)低于绝经后女性(64.24±36.05ng/mL),差异具有统计学意义(P<0.001)。在绝经前女性中,根据牙周病诊断,铁和铁蛋白的平均值之间没有统计学差异(P=0.200 和 P=0.858)。在绝经后女性中,根据牙周病诊断,血清铁蛋白平均值之间存在统计学差异(P<0.001)。绝经后女性血清铁蛋白在 % 牙周袋骨丧失=0 时为 33.93±8.65ng/mL;在牙周炎 1 期为 47.51±16.17ng/mL;在牙周炎 2 期为 72.66±18.12ng/mL;在牙周炎 3-4 期为 87.4±47.1ng/mL。
绝经后女性的血清铁蛋白值可能因牙周炎的存在或严重程度而异。