Yang Fang, Sun Xueyue, Jiang Kui
Department of Gastroenterology and Hepatology, Baodi Clinical College of Tianjin Medical University, Tianjin Baodi Hospital.
Department of Gastroenterology and Hepatology, Tianjin Medical University General Hospital.
J Clin Gastroenterol. 2025 Jan 1;59(1):1-5. doi: 10.1097/MCG.0000000000001980.
The prevalence of colonic diverticula is rising in eastern countries, possibly related to aging and the adoption of a western lifestyle. However, limited data exist regarding the distribution and endoscopic features of colonic diverticula in this population. This study aimed to assess the number, size, depth, and location of colonic diverticula in our study cohort.
We collected data from patients who underwent colonoscopy at the Endoscopy Center of Tianjin Medical University General Hospital and Bao Di Clinical College of Tianjin Medical University. We thoroughly evaluated and documented any colonic diverticula encountered during the procedures. Logistic regression analysis was employed to explore associations between participant characteristics and the presence of colonic diverticula.
Our study included a total of 27,021 eligible patients from our colonoscopy database, among whom 1529 individuals (5.67%) exhibited one or more diverticulosis. Patients with colonic diverticula (mean age: 58.6) were significantly older and exhibited a male predominance compared with those without diverticula. Cases of right-sided, left-sided, and bilateral diverticulosis were recorded in 1161 (76.0%), 170 (11.1%), and 198 patients (12.9%), respectively. Patients with right-sided diverticula (mean age: 55.2), more common in males, were younger than those with left-sided diverticula (mean age: 67.1, P < 0.05), which were more frequent in females ( P < 0.001). Individuals aged 60 years or older (odds ratio: 4.32, P < 0.001) and those with bilateral diverticulosis (odds ratio: 21.2, P < 0.001) had a higher likelihood of having a greater burden of diverticula.
Colonic diverticula in Northern China predominantly manifests as right-sided, more common in males, and associated with older age. Notably, patients with right-sided diverticulosis tend to be younger than those with left-sided diverticula. In addition, a higher burden of diverticula is more prevalent in individuals aged 60 years or older and those with a bilateral distribution pattern.
在东方国家，结肠憩室的患病率正在上升，这可能与老龄化以及西方生活方式的采用有关。然而，关于该人群中结肠憩室的分布和内镜特征的数据有限。本研究旨在评估我们研究队列中结肠憩室的数量、大小、深度和位置。
我们收集了在天津医科大学总医院内镜中心和天津医科大学宝坻临床学院接受结肠镜检查的患者的数据。我们对检查过程中发现的任何结肠憩室进行了全面评估并记录。采用逻辑回归分析来探讨参与者特征与结肠憩室存在之间的关联。
我们的研究共纳入了来自结肠镜检查数据库的27021名符合条件的患者，其中1529人（5.67%）有一个或多个憩室病。与无憩室的患者相比，有结肠憩室的患者（平均年龄：58.6岁）年龄明显更大，且以男性为主。右侧、左侧和双侧憩室病的病例分别记录在1161例（76.0%）、170例（11.1%）和198例患者（12.9%）中。右侧有憩室的患者（平均年龄：55.2岁）在男性中更常见，比左侧有憩室的患者（平均年龄：67.1岁，P<0.05）年轻，左侧憩室在女性中更常见（P<0.001）。60岁及以上的个体（优势比：4.32，P<0.001）和双侧憩室病患者（优势比：21.2，P<0.001）有更高的憩室负担可能性。
中国北方的结肠憩室主要表现为右侧，在男性中更常见，且与年龄较大有关。值得注意的是，右侧憩室病患者往往比左侧憩室病患者年轻。此外，憩室负担较高在60岁及以上的个体和双侧分布模式的患者中更为普遍。
