血小板会迁移到炎性渗出物中吗？

Do platelets migrate into inflammatory exudates?

作者信息

Ubatuba F B

出版信息

Braz J Med Biol Res. 1985;18(3):403-4.

Abstract

Rat platelets and the corresponding rabbit IgG antibodies mixed in polyester sponges implanted under the skin of normal animals caused an enhanced 24-h inflammatory response and a significant increase of prostaglandins in the exudate. These experimental results contrast with those obtained for normal rats implanted with sponges containing only IgG anti-platelet antibodies. The present experiments show that circulating platelets were not concentrated at the inflamed site and can hardly be considered of importance in acute inflammation.

摘要

将大鼠血小板与相应的兔IgG抗体混合，植入正常动物皮下的聚酯海绵中，会导致24小时炎症反应增强，渗出液中前列腺素显著增加。这些实验结果与仅植入含IgG抗血小板抗体海绵的正常大鼠所获得的结果形成对比。目前的实验表明，循环血小板不会聚集在炎症部位，在急性炎症中几乎不被认为具有重要作用。