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疟疾的血清学诊断。以伯氏疟原虫和恶性疟原虫作为间接免疫荧光试验的抗原(作者译)

[Serodiagnosis of malaria. Plasmodium berghei and P. falciparum as antigen for the indirect immune of fluorescence test (author's transl)].

作者信息

Maier W A, Piekarski G

出版信息

Immun Infekt. 1979 Jun;7(3):75-82.

PMID:383607
Abstract

Serum samples of malaria patients were investigated by the IIFT with P. berghei antigen (from mice) and P. falciparum antigen (from in vitro cultures). Both antigens were useful principally and produced approximately identical results. P. falciparum antigen produced mostly higher titres than P. berghei antigen. In cases of lack of homologous malaria antigen it can be suitable to use an antibody-free P. berghei antigen for the IIFT, especially in cases of epidemiological studies. For the individual clinical diagnosis titres of 1:64 are significant.

摘要

采用来自小鼠的伯氏疟原虫抗原和来自体外培养物的恶性疟原虫抗原,通过间接免疫荧光试验(IIFT)对疟疾患者的血清样本进行检测。两种抗原主要都很有用,且产生的结果大致相同。恶性疟原虫抗原产生的滴度大多高于伯氏疟原虫抗原。在缺乏同源疟疾抗原的情况下,使用无抗体的伯氏疟原虫抗原进行间接免疫荧光试验可能是合适的,特别是在流行病学研究中。对于个体临床诊断,滴度为1:64具有显著意义。

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