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伊朗南部代谢健康型肥胖和健康超重的患病率及其相关因素:一项基于人群的横断面研究。

Prevalence of metabolically healthy obesity and healthy overweight and the associated factors in southern Iran: A population-based cross-sectional study.

作者信息

Taherifard Erfan, Taherifard Ehsan, Jeddi Marjan, Ahmadkhani Alireza, Kelishadi Roya, Poustchi Hossein, Gandomkar Abdullah, Malekzadeh Fatemeh, Mohammadi Zahra, Molavi Vardanjani Hossein

机构信息

MD-MPH Department, School of Medicine Shiraz University of Medical Sciences Shiraz Iran.

Student Research Committee Shiraz University of Medical Sciences Shiraz Iran.

出版信息

Health Sci Rep. 2024 Feb 15;7(2):e1909. doi: 10.1002/hsr2.1909. eCollection 2024 Feb.

Abstract

BACKGROUND AND AIMS

Obesity is considered a major growing threat to public health which could negatively affect the quality of life. The current cross-sectional study was conducted to investigate the population-based prevalence of metabolically healthy obesity (MHO) and healthy overweight (MHOW) and associated factors in southern Iran.

METHODS

Baseline data from the Pars Cohort Study was analyzed. Metabolically healthy participants were identified based on the definition of the American Heart Association for the metabolic syndrome. The prevalence of MHOW and MHO and their 95% confidence intervals were estimated. Poisson regression was applied for the calculation of prevalence ratios (PRs).

RESULTS

Gender- and age-standardized prevalences of MHOW and MHO were 6.3% (6.0%-6.6%) and 2.3% (2.1%-2.5%), respectively. The following factors were associated with being MHOW compared with those with normal weight: Being younger, female gender (1.31, 1.20-1.43), higher socioeconomic status, being noncurrent cigarette smoker (1.27, 1.11-1.45), low level of physical activity (1.14, 1.03-1.25), having normal overweight during adolescence, and overweight (1.35, 1.24-1.48) or obesity (1.68, 1.53-1.86) during young adulthood. We also found strong associations between MHO and younger age groups, female gender (2.87, 2.40-3.42), being married (1.57, 1.08-2.27), Fars ethnicity (1.25, 1.10-1.43), higher socioeconomic status, ever use of tobacco (1.14, 1.00-1.30), never use of opium (1.85, 1.19-2.86), lower physical activity (1.45, 1.20-1.72), being normal weight in 15-year body pictogram and being overweight (1.87, 1.59-2.20) or obese (3.20, 2.74-3.72) in 30-year body pictogram when considering those with normal weight or MHO.

CONCLUSION

Potentially modifiable factors including physical activity should be more emphasized. Furthermore, our study issued that it would be more reasonable that the prevention of unhealthy obesity be initiated before the development of MHO, where there are more protective factors and they could be more effective.

摘要

背景与目的

肥胖被认为是对公众健康日益严重的主要威胁,会对生活质量产生负面影响。本横断面研究旨在调查伊朗南部基于人群的代谢健康肥胖(MHO)和健康超重(MHOW)的患病率及其相关因素。

方法

分析了帕尔斯队列研究的基线数据。根据美国心脏协会对代谢综合征的定义确定代谢健康参与者。估计了MHOW和MHO的患病率及其95%置信区间。应用泊松回归计算患病率比(PRs)。

结果

MHOW和MHO的性别和年龄标准化患病率分别为6.3%(6.0%-6.6%)和2.3%(2.1%-2.5%)。与正常体重者相比,以下因素与MHOW相关:年龄较小、女性(1.31,1.20-1.43)、社会经济地位较高、非当前吸烟者(1.27,1.11-1.45)、身体活动水平较低(1.14,1.03-1.25)、青春期正常超重以及青年期超重(1.35,1.24-1.48)或肥胖(1.68,1.53-1.86)。我们还发现MHO与较年轻年龄组、女性(2.87,2.40-3.42)、已婚(1.57,1.08-2.27)、法尔斯族裔(1.25,1.10-1.43)、社会经济地位较高、曾经使用烟草(1.14,1.00-1.30)、从不使用鸦片(1.85,1.19-2.86)、身体活动水平较低(1.45,1.20-1.72)、15岁时体重正常以及30岁时超重(1.87,1.59-2.20)或肥胖(3.20,2.74-3.72)(考虑正常体重或MHO者)之间存在密切关联。

结论

应更加强调包括身体活动在内的潜在可改变因素。此外,我们的研究表明,在MHO发展之前启动不健康肥胖的预防可能更为合理,此时存在更多保护因素且可能更有效。

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