平民和军事艰苦环境下腹部不可压缩性躯干出血的管理:一项范围综述
Management of non-compressible torso hemorrhage of the abdomen in civilian and military austere environments: a scoping review.
作者信息
Adams Donald, McDonald Paige L, Holland Seth, Merkle Alexander B, Puglia Christen, Miller Becky, Allison Deidre D, Moussette Christina, Souza Christopher J, Nunez Timothy, van der Wees Philip
机构信息
Translational Health Science, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Clinical Research and Leadership Department, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
出版信息
Trauma Surg Acute Care Open. 2024 Feb 14;9(1):e001189. doi: 10.1136/tsaco-2023-001189. eCollection 2024.
BACKGROUND
Non-compressible abdominal hemorrhage (NCAH) is the leading cause of potentially preventable deaths in both civilian and military austere environments, and an improvement in mortality due to this problem has not been demonstrated during the past quarter century. Several innovations have been developed to control hemorrhage closer to the point of injury.
OBJECTIVE
This review assessed NCAH interventions in civilian and military settings, focusing on austere environments. It identified innovations, effectiveness, and knowledge gaps for future research.
METHODOLOGY
The Joanna Briggs Institute for Evidence Synthesis methodology guided this scoping review to completion. Studies evaluating NCAH with human participants in civilian and military austere environments that were eligible for inclusion were limited to English language studies published between December 1990 and January 2023. The PCC (Participant, Concept, Context) framework was used for data synthesis. Deductive and inductive thematic analyses were used to assess the literature that met inclusion criteria, identify patterns/themes to address the research questions and identify common themes within the literature. A stakeholder consultation was conducted to review and provide expert perspectives and opinions on the results of the deductive and inductive thematic analyses.
RESULTS
The literature search identified 868 articles; 26 articles met the inclusion criteria. Textual narrative analysis of the 26 articles resulted in the literature addressing four main categories: NCAH, penetrating abdominal trauma, resuscitative endovascular balloon occlusion of the aorta (REBOA), and ResQFoam. The deductive thematic analysis aimed to answer three research questions. Research question 1 addressed the effectiveness of REBOA, damage control resuscitation, and damage control surgery in managing NCAH in austere environments. No effectiveness studies were found on this topic. Research question 2 identified three knowledge gaps in NCAH management in austere environments. The analysis identified early hemorrhage control, prehospital provider decision-making ability, and REBOA implementation as knowledge gaps in NCAH. Research question 3 identified five innovations that may affect the management of NCAH in the future: transport of patients, advanced resuscitative care, expert consultation, REBOA implementation, and self-expanding foam implementation. The inductive thematic analysis resulted in four recurrent themes from the literature: prehospital care, decision-making, hemorrhage control, and mortality in NCAH. During the stakeholders' consultation, the results of the deductive and inductive thematic analyses were reviewed and agreed on by the stakeholders. Special emphasis and discussion were given to prehospital management, expert opinions in the prehospital environment, decision-making in the prehospital environment, transport and resuscitation in the prehospital setting, REBOA, alternative discussion for research, and research gaps.
CONCLUSION
NCAH is still a significant cause of preventable death in both military and civilian austere environments, even with ongoing research and interventions aimed at extending survival in such conditions. This scoping review has identified several potential concepts that could reduce the mortality associated with a preventable cause of death due to hemorrhage in austere environments.
背景
不可压缩性腹部出血(NCAH)是民用和军事严峻环境中潜在可预防死亡的主要原因,在过去四分之一世纪里,因这一问题导致的死亡率并未得到改善。人们已经开发了多种创新方法,以便在更接近损伤部位的地方控制出血。
目的
本综述评估了民用和军事环境中针对NCAH的干预措施,重点关注严峻环境。它确定了创新方法、有效性以及未来研究的知识空白。
方法
乔安娜·布里格斯循证综合研究所的方法指导了本综述的完成。评估民用和军事严峻环境中人类参与者NCAH的研究仅限于1990年12月至2023年1月发表的英文研究。采用PCC(参与者、概念、背景)框架进行数据综合。使用演绎和归纳主题分析来评估符合纳入标准的文献,识别模式/主题以解决研究问题,并确定文献中的共同主题。进行了利益相关者咨询,以审查并提供关于演绎和归纳主题分析结果的专家观点和意见。
结果
文献检索共识别出868篇文章;26篇文章符合纳入标准。对这26篇文章进行的文本叙述分析得出,文献涉及四个主要类别:NCAH、穿透性腹部创伤、主动脉复苏性血管内球囊阻断术(REBOA)和ResQFoam。演绎主题分析旨在回答三个研究问题。研究问题1探讨了REBOA、损伤控制复苏和损伤控制手术在严峻环境中管理NCAH的有效性。未找到关于该主题的有效性研究。研究问题2确定了严峻环境中NCAH管理的三个知识空白。分析确定早期出血控制、院前提供者决策能力和REBOA实施是NCAH中的知识空白。研究问题3确定了可能影响未来NCAH管理的五项创新:患者转运、高级复苏护理、专家咨询、REBOA实施和自膨胀泡沫实施。归纳主题分析从文献中得出四个反复出现的主题:院前护理、决策、出血控制和NCAH中的死亡率。在利益相关者咨询期间,利益相关者对演绎和归纳主题分析的结果进行了审查并达成一致。特别强调并讨论了院前管理、院前环境中的专家意见、院前环境中的决策、院前环境中的转运和复苏、REBOA、研究的替代讨论以及研究空白。
结论
即使有旨在延长此类情况下生存率的持续研究和干预措施,NCAH在军事和民用严峻环境中仍然是可预防死亡的重要原因。本综述确定了几个潜在概念,这些概念可以降低严峻环境中因可预防的出血性死亡原因导致的死亡率。