Department of Radiation Oncology and Image-Applied Therapy, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Division of Clinical Radiology Service, Kyoto University Hospital, Kyoto, Japan.
J Appl Clin Med Phys. 2024 Jul;25(7):e14307. doi: 10.1002/acm2.14307. Epub 2024 Feb 16.
For patient-specific quality assurance (PSQA) for small targets, the dose resolution can change depending on the characteristics of the dose calculation algorithms.
This study aimed to evaluate the influence of the dose calculation algorithms Acuros XB (AXB), anisotropic analytical algorithm (AAA), photon Monte Carlo (pMC), and collapsed cone (CC) on a helical diode array using volumetric-modulated arc therapy (VMAT) for small targets.
ArcCHECK detectors were inserted with a physical depth of 2.9 cm from the surface. To evaluate the influence of the dose calculation algorithms for small targets, rectangular fields of 2×100, 5×100, 10×100, 20×100, 50×100, and 100×100 mm were irradiated and measured using ArcCHECK with TrueBeam STx. A total of 20 VMAT plans for small targets, including the clinical sites of 19 brain metastases and one spine, were also evaluated. The gamma passing rates (GPRs) were evaluated for the rectangular fields and the 20 VMAT plans using AXB, AAA, pMC, and CC.
For rectangular fields of 2×100 and 5×100 mm, the GPR at 3%/2 mm of AXB was < 50% because AXB resulted in a coarser dose resolution with narrow beams. For field sizes > 10×100 mm2, the GPR at 3%/2 mm was > 88.1% and comparable for all dose calculation algorithms. For the 20 VMAT plans, the GPRs at 3%/2 mm were 79.1 ± 15.7%, 93.2 ± 5.8%, 94.9 ± 4.1%, and 94.5 ± 4.1% for AXB, AAA, pMC, and CC, respectively.
The behavior of the dose distribution on the helical diode array differed depending on the dose calculation algorithm for small targets. Measurements using ArcCHECK for VMAT with small targets can have lower GPRs owing to the coarse dose resolution of AXB around the detector area.
对于特定于患者的质量保证(PSQA)的小靶区,剂量分辨率可能会因剂量计算算法的特征而改变。
本研究旨在评估 Acuros XB(AXB)、各向异性解析算法(AAA)、光子蒙特卡罗(pMC)和锥形束算法(CC)这 4 种剂量计算算法对小靶区螺旋 Diode 阵列使用容积调强弧形治疗(VMAT)的影响。
在离表面 2.9cm 的深度插入 ArcCHECK 探测器。为了评估小靶区剂量计算算法的影响,使用 TrueBeam STx 照射并测量了 2×100、5×100、10×100、20×100、50×100 和 100×100mm 的矩形射野,以及 19 个脑转移瘤和 1 个脊柱的小靶区 20 个 VMAT 计划。使用 AXB、AAA、pMC 和 CC 对矩形射野和 20 个 VMAT 计划进行了γ通过率(GPR)评估。
对于 2×100 和 5×100mm 的矩形射野,AXB 的 3%/2mm 处 GPR<50%,因为 AXB 导致窄束的剂量分辨率更粗糙。对于大于 10×100mm2 的射野尺寸,3%/2mm 的 GPR>88.1%,且对于所有剂量计算算法都是可比的。对于 20 个 VMAT 计划,AXB、AAA、pMC 和 CC 的 3%/2mm 的 GPR 分别为 79.1±15.7%、93.2±5.8%、94.9±4.1%和 94.5±4.1%。
对于小靶区,剂量计算算法的行为会导致螺旋 Diode 阵列上的剂量分布不同。由于 AXB 在探测器区域周围的剂量分辨率较粗糙,使用 ArcCHECK 对小靶区 VMAT 进行测量可能会导致较低的 GPR。