Erasmus J A, Bergh E C
J S Afr Vet Assoc. 1985 Dec;56(4):205-8.
The effect of repeated vaccination of ram lambs with Brucella melitensis Rev 1 vaccine was studied in relation to complement fixation titres. The presence of Brucella organisms in semen and changes in neutrophil densities of the semen were also studied. A survey of the incidence of ovine brucellosis in the Winburg district on the basis of a clinical examination of rams and the complement fixation test is also reported on. Repeated vaccination of ram lambs with Rev 1 vaccine resulted in high complement fixation titres for Brucella abortus in all cases and slight Brucella ovis titres in some cases. Neither Brucella organisms, nor increased numbers of neutrophils could be found in semen samples collected from the experimental animals. The incidence of ovine brucellosis in commercial and stud flocks in the Winburg district was in the order of 2%. As a fairly high incidence of brucellosis occurred in 2 stud Döhne merino flocks where ram lambs are vaccinated with Rev 1 at weaning, the administration thereof in this breed should take place at an earlier age. A second dosage at weaning should not have any disadvantageous effects. In order to protect newly vaccinated ram lambs from contracting brucellosis from older, infected cases, the separation of age groups is essential. The incidence of clinically detectable testicular lesions in rams from the Winburg district was in the order of 2%.
研究了用布鲁氏菌羊种1号疫苗对雄性羔羊进行重复接种与补体结合滴度的关系。还研究了精液中布鲁氏菌的存在情况以及精液中嗜中性粒细胞密度的变化。此外，还报告了基于对公羊的临床检查和补体结合试验对温堡地区绵羊布鲁氏菌病发病率的调查。用1号疫苗对雄性羔羊进行重复接种，在所有情况下均导致针对流产布鲁氏菌的高补体结合滴度，在某些情况下还导致轻度的绵羊布鲁氏菌滴度。从实验动物采集的精液样本中既未发现布鲁氏菌，也未发现嗜中性粒细胞数量增加。温堡地区商业羊群和种羊场中绵羊布鲁氏菌病的发病率约为2%。由于在2个多hne美利奴种羊场中，雄性羔羊在断奶时用1号疫苗接种后布鲁氏菌病发病率相当高，因此在该品种中应在更早的年龄进行接种。断奶时的第二次剂量不应有任何不利影响。为了保护新接种的雄性羔羊不被 older、受感染的病例感染布鲁氏菌病，必须对年龄组进行隔离。温堡地区公羊中临床可检测到的睾丸病变发病率约为2%。
