Clemens Christoph R, Alten Florian, Eter Nicole, Helbig Horst, Märker David A
Universitäts-Augenklinik Münster, Domagkstr. 15, 48149, Münster, Deutschland.
Universitäts-Augenklinik Regensburg, Regensburg, Deutschland.
Ophthalmologie. 2024 May;121(5):385-390. doi: 10.1007/s00347-024-01997-8. Epub 2024 Feb 16.
Intravitreal medication injections are an efficient and low-risk delivery technique for treating various retinal diseases. Rare serious complications include increased intraocular pressure, vitreous hemorrhage, retinal tears and detachment, intraocular inflammation and endophthalmitis. In the case series presented here, we report iatrogenic lens injuries caused by inadequate performance of intravitreal injections.
A multicenter data collection of patients treated with intravitreal injections with visible iatrogenic lens defects from 2016 to 2023 was retrospectively performed.
Lens trauma after intravitreal injections was identified in six cases (69.3±6.5 years). While five cases were observed after anti-VEGF therapy, we identified lens injury after dexamethasone implantation in one patient.
Iatrogenic lens injury during intravitreal injection is preventable with the correct injection technique. Knowledge of individual axis length and lens status also helps to avoid this complication.
玻璃体内药物注射是治疗各种视网膜疾病的一种有效且低风险的给药技术。罕见的严重并发症包括眼压升高、玻璃体积血、视网膜裂孔和脱离、眼内炎症和眼内炎。在本文介绍的病例系列中，我们报告了因玻璃体内注射操作不当导致的医源性晶状体损伤。
对2016年至2023年接受玻璃体内注射且存在可见医源性晶状体缺陷的患者进行多中心数据收集。
在6例患者（69.3±6.5岁）中发现玻璃体内注射后晶状体损伤。其中5例在抗VEGF治疗后观察到，1例患者在植入地塞米松后出现晶状体损伤。
采用正确的注射技术可预防玻璃体内注射期间的医源性晶状体损伤。了解个体眼轴长度和晶状体状态也有助于避免这种并发症。
