Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Kettegaard Allé 30, 2650 Hvidovre, Denmark.
Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Kettegaard Allé 30, 2650 Hvidovre, Denmark; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Øster Farimagsgade 5, 1353 Copenhagen, Denmark.
Maturitas. 2024 May;183:107937. doi: 10.1016/j.maturitas.2024.107937. Epub 2024 Feb 9.
Women living with human immunodeficiency virus (HIV) today have life expectancies comparable to the general female population, leading to a growing number transitioning through menopause. Recent studies have highlighted healthcare professionals' lack of confidence in managing menopause in women with HIV, raising concerns about potential mismanagement. This review explores and compares information on menopause management in HIV-specific and general guidelines, with the aim of identifying disparities and assessing the comprehensiveness of HIV guidelines. The focus is on three key areas: the diagnosis of menopause, and the assessment and treatment of menopausal symptoms. Additionally, the review evaluates the usage and characteristics of menopausal symptom assessment scales known to have been used in studies involving women living with HIV. In total, five HIV and six general menopause management guidelines, published between 2015 and 2023, were identified through medical databases, internet search engines and searches of reference lists. Five menopausal symptom assessment scales were also included for review. The findings suggest minimal differences in recommendations for treating menopausal symptoms. The HIV guidelines include recommendations on screening for menopause, and some raise awareness of the possibility of drug-to-drug interactions, but none offers guidance on how to diagnose menopause or how to differentiate between HIV-related and menopause-related symptoms. Upon examining the characteristics of the menopausal symptom assessment scales, we found that none had been validated specifically for women with HIV. In conclusion, this review advocates for the development of a comprehensive guideline that addresses all relevant factors in managing menopause in women with HIV.
如今，患有人类免疫缺陷病毒（HIV）的女性预期寿命可与普通女性人群相媲美，这导致越来越多的女性进入更年期。最近的研究强调了医疗保健专业人员在管理 HIV 女性更年期方面缺乏信心，这引发了对潜在管理不善的担忧。本综述探讨并比较了 HIV 特异性和一般指南中关于更年期管理的信息，旨在确定差异并评估 HIV 指南的全面性。重点关注三个关键领域：更年期的诊断，以及更年期症状的评估和治疗。此外，该综述还评估了已知在涉及 HIV 女性的研究中使用的更年期症状评估量表的使用情况和特点。总共通过医学数据库、互联网搜索引擎和参考文献列表，确定了五份 HIV 和六份一般更年期管理指南，这些指南均在 2015 年至 2023 年期间发表。还包括了五份更年期症状评估量表进行综述。研究结果表明，治疗更年期症状的建议差异很小。HIV 指南包括更年期筛查的建议，其中一些指南提高了对药物相互作用可能性的认识，但没有指南提供关于如何诊断更年期或如何区分与 HIV 相关和与更年期相关的症状的指导。在检查更年期症状评估量表的特点后，我们发现没有一个量表是专门针对 HIV 女性制定的。总之，本综述提倡制定一份全面的指南，以解决 HIV 女性更年期管理中所有相关因素。
