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两姐妹中的特发性颅内高压。

Idiopathic intracranial hypertension in two twin sisters.

机构信息

University of Otago, Dunedin, New Zealand

University of Otago, Dunedin, New Zealand.

出版信息

BMJ Case Rep. 2024 Feb 17;17(2):e256423. doi: 10.1136/bcr-2023-256423.

Abstract

Idiopathic intracranial hypertension (IIH) is a condition of unknown aetiology characterised by an increase in the intracranial pressure. Familial cases of IIH are rare and not well-understood. We present two monozygotic twins who developed IIH two years apart. The case involves two monozygotic female twins developing IIH in their 50s. They presented with a history of blurry vision and headaches. The diagnosis included the neurological, radiological and ophthalmological examination, excluding other causes. Both patients received treatment with acetazolamide, successfully resolving the papilloedema and restoring a normal visual field. This case highlights the occurrence of IIH among twins presenting at similar periods, emphasising the potential genetic influence. Clinicians should alert and educate the family regarding the risk factors and potential symptoms of this condition in the unlikely occurrence that other family members are affected.

摘要

特发性颅内高压(IIH)是一种病因不明的疾病,其特征是颅内压升高。IIH 的家族病例很少见,也未被很好地理解。我们报告了两例异卵双胞胎,她们在两年内相继患上 IIH。该病例涉及两名 50 多岁的同卵双胞胎女性患上 IIH。她们有视力模糊和头痛的病史。诊断包括神经学、放射学和眼科检查,排除了其他原因。两名患者均接受乙酰唑胺治疗,成功解决了视乳头水肿并恢复了正常的视野。本病例强调了双胞胎在相似时期出现 IIH 的可能性,提示存在潜在的遗传影响。如果其他家庭成员受到影响,临床医生应警惕并向其家属告知该病症的危险因素和潜在症状。

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Idiopathic intracranial hypertension in two twin sisters.两姐妹中的特发性颅内高压。
BMJ Case Rep. 2024 Feb 17;17(2):e256423. doi: 10.1136/bcr-2023-256423.
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本文引用的文献

10
Idiopathic intracranial hypertension: consensus guidelines on management.特发性颅内高压:管理共识指南。
J Neurol Neurosurg Psychiatry. 2018 Oct;89(10):1088-1100. doi: 10.1136/jnnp-2017-317440. Epub 2018 Jun 14.

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